DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Samtor and bmt2

DIOPT Version :9

Sequence 1:	NP_611943.1	Gene:	Samtor / 37934	FlyBaseID:	FBgn0035035	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001070615.1	Gene:	bmt2 / 558558	ZFINID:	ZDB-GENE-060825-17	Length:	393	Species:	Danio rerio

Alignment Length:	326	Identity:	103/326 - (31%)
Similarity:	157/326 - (48%)	Gaps:	53/326 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EEHQRLASIVKSCHESLRQLTKEYG-ATAAWQEHTSPRNAKQLAEYAKAMKQLAAIWETNDGKVE 67
            :|.::|:.:|||.|..||:...|.| ....|:||.  .:.:.|:|||.|||.||    .|....:
Zfish    30 QEQEKLSGVVKSVHRKLRRKYIEVGDFDKIWREHC--EDEQTLSEYAMAMKNLA----DNHWANK 88

  Fly    68 LQARSRIKWAIDYITKYFFTEGI--YLQKRQREQRLLESYRAEGKLGEVQCRLMEEPPD------ 124
            .:...||:|......:||...|:  .|:|.::..|...:..|...        ...||.
Zfish    89 CEGEGRIEWCRSVCQEYFQDGGMRRVLEKDEKSARHATAGNANTD--------TNAPPQLSSIST 145

  Fly   125 -------RLHVLDVGSCFNPFSSAPHLEVTALDLCPATEDVLQADFLKVEVVPGIREP------- 175
                   ::.:||||||||||..........:|:.||.|.|.:.|||.::    :::|
Zfish   146 SSTFQLGKIRLLDVGSCFNPFLKFDEFLTVGIDIVPAVESVYKCDFLNLQ----LQQPLQLASDA 206

  Fly   176 ------ELEEGSVRRLPASHYECVIFSLLLEYMPSAEQRLQCCLQAYDLLLPEGILVLITPDSQH 234
                  :| .|.:..|||..:..|:|||||.|.||..||..||.:|::||...|:|::|||||.|
Zfish   207 LDAFLRQL-RGPIDALPAELFHVVVFSLLLSYFPSPYQRWLCCKKAHELLTLNGLLLIITPDSSH 270

  Fly   235 VGKNAHLMKNWRYSLARIGLLRVRFEKLPHISCMVFRKAISRELSQHWASIHREEGMCEEIRIPQ 299
            .|::|.:|::||.::..:|..|.::.|..|:..:.||| :|...|....|    ....|.:.|||
Zfish   271 QGRHALMMRSWRVAVESLGFKRYKYVKFSHMHLIAFRK-VSPTTSSDLVS----RNYPEMLYIPQ 330

  Fly   300 D 300
            |
Zfish   331 D 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Samtor	NP_611943.1	AdoMet_MTases	102..>223	CDD:302624	43/146 (29%)
Samtor	NP_611943.1	AdoMet_MTases	<186..266	CDD:302624	35/79 (44%)
bmt2	NP_001070615.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..141		4/30 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	362..393
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28J7Q
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H34695
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4380
OMA	1	1.010	-	-		QHG52239
OrthoDB	1	1.010	-	-		D360379at33208
OrthoFinder	1	1.000	-	-		FOG0007792
OrthoInspector	1	1.000	-	-		oto40988
orthoMCL	1	0.900	-	-		OOG6_108162
Panther	1	1.100	-	-	LDO	PTHR21008
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4806
SonicParanoid	1	1.000	-	-		X5737
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800