DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Samtor and Bmt2

DIOPT Version :9

Sequence 1:	NP_611943.1	Gene:	Samtor / 37934	FlyBaseID:	FBgn0035035	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001102691.1	Gene:	Bmt2 / 500034	RGDID:	1588441	Length:	403	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	104/328 - (31%)
Similarity:	160/328 - (48%)	Gaps:	48/328 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EHQRLASIVKSCHESLRQLTKEYG-ATAAWQEHTSPRNAKQLAEYAKAMKQLAAIWETNDGKVEL 68
            |.::|:.:|||.|..||:..:|.| ....|:||.  .:|:.|.|||.|||.||    .|......
  Rat    30 EQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHC--EDAETLCEYAVAMKNLA----DNHWAKTC 88

  Fly    69 QARSRIKWAIDYITKYFFTEGIYLQKRQREQRLL------------ESYRAEGKLGEVQCRLME- 120
            :...||:|......:||...|......:.|:|.:            ||.:.||.|..:.....|
  Rat    89 EGEGRIEWCCSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNVHESSKLEGPLTNLSFTSPEF 153

  Fly   121 -----EPPDRLHVLDVGSCFNPFSSAPHLEVTALDLCPATEDVLQADFLKVEVVPGIREP-ELEE 179
                 :...::.:||||||||||..........:|:.||.|.|.:.|||.::    :::| :|.:
  Rat   154 ITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQ----LQQPLQLAQ 214

  Fly   180 GS-----------VRRLPASHYECVIFSLLLEYMPSAEQRLQCCLQAYDLLLPEGILVLITPDSQ 233
            .:           :..||...:..|:|||||.|.||..||..||.:|::||:..|:|::|||||.
  Rat   215 DAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSS 279

  Fly   234 HVGKNAHLMKNWRYSLARIGLLRVRFEKLPHISCMVFRKAISRELSQHWASIHRE-EGMCEEIRI 297
            |..::|.:||:|:.::..:|..|.::.|..|:..|.|||...:..|.   .:.|. .||   :.|
  Rat   280 HQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKTSLKTTSD---LVSRNYPGM---LYI 338

  Fly   298 PQD 300
            |||
  Rat   339 PQD 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Samtor	NP_611943.1	AdoMet_MTases	102..>223	CDD:302624	44/150 (29%)
Samtor	NP_611943.1	AdoMet_MTases	<186..266	CDD:302624	33/79 (42%)
Bmt2	NP_001102691.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346114
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28J7Q
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H34695
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4673
OMA	1	1.010	-	-		QHG52239
OrthoDB	1	1.010	-	-		D360379at33208
OrthoFinder	1	1.000	-	-		FOG0007792
OrthoInspector	1	1.000	-	-		oto96489
orthoMCL	1	0.900	-	-		OOG6_108162
Panther	1	1.100	-	-	LDO	PTHR21008
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5737
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770