DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3565 and EFCAB1

DIOPT Version :9

Sequence 1:	NP_611942.1	Gene:	CG3565 / 37933	FlyBaseID:	FBgn0035034	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_078869.1	Gene:	EFCAB1 / 79645	HGNCID:	25678	Length:	211	Species:	Homo sapiens

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	93/214 - (43%)	Gaps:	41/214 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 FSHNELISIVMLYHKFVLVNGPRAKYMTI----QQLSALMELLFEIVDRDLIATIVYRIAHTPGS 93
            |:..|:..::.|::.  ||.|...:.:.:    .....::.:.|.:.| |:|...|:|     |.
Human    20 FNKFEVNCLIKLFYD--LVGGVERQGLVVGLDRNAFRNILHVTFGMTD-DMIMDRVFR-----GF 76

  Fly    94 RPPDFFSDKHIHLESFVRLFTVYFTKDLQLKMEFAFSVYDKSDSKQLNGEQVGFFVGK--FF--- 153
               |..:|..:::..::...:::....|:.||::.|.|:|      |||:.   |:.|  .|
Human    77 ---DKDNDGCVNVLEWIHGLSLFLRGSLEEKMKYCFEVFD------LNGDG---FISKEEMFHML 129

  Fly   154 --------ESEDEDESIELRLDMKEMLFLKFDLDKDTNIGVDEYYEVVRRQPMLLECFGRVFP-P 209
                    ..||.||.|:   |:.|:...|.|.|.|..:...:|...||.:.:|||.||...| |
Human   130 KNSLLKQPSEEDPDEGIK---DLVEITLKKMDHDHDGKLSFADYELAVREETLLLEAFGPCLPDP 191

  Fly   210 NPQMEVLALCANVMSWFDD 228
            ..|||..|......:.|:|
Human   192 KSQMEFEAQVFKDPNEFND 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3565	NP_611942.1	None
EFCAB1	NP_078869.1	EFh_PEF	<48..170	CDD:330173	32/142 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1331864at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.980