DRSC/TRiP Functional Genomics Resources

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Protein Alignment pio and nyo

DIOPT Version :10

Sequence 1:NP_726461.1 Gene:pio / 37929 FlyBaseID:FBgn0020521 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_651871.2 Gene:nyo / 43716 FlyBaseID:FBgn0039852 Length:805 Species:Drosophila melanogaster


Alignment Length:506 Identity:109/506 - (21%)
Similarity:183/506 - (36%) Gaps:135/506 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 IAALTTHAAQIPTAMKDAQSSLSDAIAAAEAEVASTSKPAVEPSVRIKCLSGSMLITIKDAPPNH 83
            :..|:.|:.   ..:.|......|...||..|:::..      :|.|:|.||.|:..|:.:.   
  Fly   344 VCRLSHHSR---ATLTDVMDPYLDVPEAATYELSACY------NVSIECRSGEMITKIRTSK--- 396

  Fly    84 ETGLFSGMIYPKGLSK------NSTCLSEYRDHVGSLRYKLPLRSCNTMPKETDDGGIEFFNTIV 142
               ||.|.:|.||..|      |::...::|.....|       .||.  :::..|  .:.|.||
  Fly   397 ---LFDGKVYAKGAPKSCAVNVNNSLEFDFRMGYNDL-------ECNV--RQSAYG--RYMNDIV 447

  Fly   143 LQPHLKLITDLGRGYHVRCAYKSRDAAMKPKKYLRKHAQKPQAFRSDDRREYGRSLDKQQDDDLD 207
            :|.|..::|....|..|.|.|.     :..|..|                         .|.||.
  Fly   448 IQHHDMIVTSSDLGLAVSCQYD-----LTNKTVL-------------------------NDVDLG 482

  Fly   208 EEDVYDANAPTQEEDVTNNEIPMPGCHMKIYNDEHKIADDVK----IGDPLTIVISI-DKQKVYG 267
            .....:::.   .|::|   |..|...|||.:.:   ..|:|    :||||.:...| :....|.
  Fly   483 VTGEIESSL---SEEIT---IDSPNVIMKITSRD---GSDMKRMAEVGDPLALRFEIVEPNSPYE 538

  Fly   268 LHVTDCIVRDGLGWGEQRLVGEDGCPMDNEIMGQFNYTQDRLAAN-----VTFPAHKFPYTTSVY 327
            :.|.:.:..||....|..|:..:|||.|..|||    |..:||.|     ..|.|.|||.:..|.
  Fly   539 IFVRELVAMDGSDSAEITLIDANGCPTDQYIMG----TIQKLAQNRKVLLSQFDAFKFPSSEVVQ 599

  Fly   328 YQCNVRLC--ALEDPTCQEAPQCSGK--------RPKRQAAADSKEEDGLPAT------------ 370
            ::..|..|  ..|...|......||:        |.||.....:...:.|.:|            
  Fly   600 FRALVTPCIPRCEPVICDSEDGASGELKSLVSYGRKKRSVLNGTDGAEFLISTRHRRDVGPVDDN 664

  Fly   371 IEVFSGLYVNE----------NENANDS-DEDAVYKEKTLDDALCVSQRTFAIAIAIAGLILMLA 424
            |.:...:.:.:          ..:.||| ..:..|.....|...|::    ...:.:||.:.:||
  Fly   665 ILLMQSIQITDKFGFQPEDGTTTHGNDSGPHEKAYAGVAQDKLTCLN----GYGLIMAGALFLLA 725

  Fly   425 VVA--AVLCIMARRSTK-----------TVSNSGSSIYSGPYTNTAFSHSS 462
            .::  .:...:.||::|           |::....::..||..|::...|:
  Fly   726 QLSIFGIWKTVQRRTSKERYLYQHEPTPTITYGAPTMLYGPPPNSSAGSSA 776

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pioNP_726461.1 ZP 66..349 CDD:214579 74/300 (25%)
nyoNP_651871.2 PAN_1 121..198 CDD:459635
PAN_AP_HGF 208..286 CDD:238532
PAN_1 295..358 CDD:459635 2/16 (13%)
ZP 382..618 CDD:214579 74/295 (25%)
Blue background indicates that the domain is not in the aligned region.

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