DRSC/TRiP Functional Genomics Resources

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Protein Alignment pio and mey

DIOPT Version :10

Sequence 1:NP_726461.1 Gene:pio / 37929 FlyBaseID:FBgn0020521 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_651870.3 Gene:mey / 43715 FlyBaseID:FBgn0039851 Length:774 Species:Drosophila melanogaster


Alignment Length:473 Identity:112/473 - (23%)
Similarity:167/473 - (35%) Gaps:144/473 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 IAALTTHAAQIPTAMKDAQSSLSDAIAAAEAEVASTSKPAVEPSVRIKCLSGSMLITIKDAPPNH 83
            :..|:.|:....|.:.:...|:         |.|:|.:.:...:|.|.|.||.|:..|:.:.   
  Fly   369 VCRLSHHSRATLTDLSEPYLSI---------EEAATYEQSACYNVSIDCRSGEMITKIRTSK--- 421

  Fly    84 ETGLFSGMIYPKGLSKNSTCLSEYRDHVGSLRYKLPLR----SCNTMPKETDDGGIEFFNTIVLQ 144
               ||.|.:|.||..|  :|.....:   ||.:.|.:|    .||.  :::..|  .:.|.||:|
  Fly   422 ---LFDGKVYAKGAPK--SCAVNVNN---SLEFDLKMRYNDLECNV--RQSAYG--RYMNDIVIQ 474

  Fly   145 PHLKLITDLGRGYHVRCAYKSRDAAMKPKKYLRKHAQKPQAFRSDDRREYGRSLDKQQDDDLDEE 209
            .|..::|....|..|.|.|                                         ||..:
  Fly   475 HHDMIVTSSDLGLAVSCQY-----------------------------------------DLTNK 498

  Fly   210 DV---YDANAPTQEEDVTNNEI--PMPGCHMKIY----NDEHKIADDVKIGDPLTIVISI-DKQK 264
            .|   .|.....:.|...:.||  ..|...|||.    :|..:||:   :||||.:...| |...
  Fly   499 TVVNNVDLGVTGEIESTLSEEIIVDSPNVIMKITARDGSDMKRIAE---VGDPLALRFEIVDANS 560

  Fly   265 VYGLHVTDCIVRDGLGWGEQRLVGEDGCPMDNEIMGQFNYTQDRLAAN-----VTFPAHKFPYTT 324
            .|.:.|.:.:..||....|..|:..:|||.|..||.    ...:||.|     ..|.|.|||.:.
  Fly   561 PYEIFVRELVAMDGTDSAEITLIDANGCPTDQYIMS----AMQKLANNRKVLLSQFDAFKFPSSE 621

  Fly   325 SVYYQCNVRLCALEDPTCQEAPQC--------------------------------SGKRPKR-- 355
            .|.::..|..|.   |.| |...|                                ..:|.||  
  Fly   622 LVQFRALVTPCI---PRC-EPVICDNDENGELKSLLSYGRRKRSVLNGTDGVELAIKSERQKRDV 682

  Fly   356 --QAAADSKEEDGLPATIEV-----FSGLYVNENENANDSDEDAVYKEK----TLDDALCVSQRT 409
              |||.|  |...|..:|::     |:|........:.....|.:.|.:    |..|. |::...
  Fly   683 SHQAAGD--ENILLVQSIQITDKFAFNGADAPGGSGSEAGGLDGLAKLQLDLGTKSDT-CINGYG 744

  Fly   410 FAIAIAIAGLILMLAVVA 427
            |.||.|:. |:|.|.|:|
  Fly   745 FIIAGALF-LLLQLTVIA 761

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pioNP_726461.1 ZP 66..349 CDD:214579 77/333 (23%)
meyNP_651870.3 PRK07003 <28..>142 CDD:235906
PAN_1 146..223 CDD:459635
PAN_AP_HGF 233..311 CDD:238532
PAN_1 320..399 CDD:459635 7/38 (18%)
ZP 408..642 CDD:214579 76/300 (25%)
Blue background indicates that the domain is not in the aligned region.

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