DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pio and CG17111

DIOPT Version :9

Sequence 1:	NP_001163295.1	Gene:	pio / 37929	FlyBaseID:	FBgn0020521	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_651119.2	Gene:	CG17111 / 42727	FlyBaseID:	FBgn0039048	Length:	792	Species:	Drosophila melanogaster

Alignment Length:	481	Identity:	103/481 - (21%)
Similarity:	176/481 - (36%)	Gaps:	116/481 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QSSLSDAIAAAEAEVASTSKPAV---EPSV---RIKCLSGSML-----ITIKDAPPNHETGLFSG 90
            |.|||:.:..:| ::.|....::   |.||   |:|||...:.     :|||..|.:    .|.|
  Fly   312 QLSLSECLLHSE-DIVSLGPRSLKLRENSVYMRRVKCLDVRVFCTRDEMTIKYNPKD----WFVG 371

  Fly    91 MIYPKGLSKNSTCLSEYRDHVGSLRYKLPLRS------CNTMP--KETDDGGIEFFNT-IVLQPH 146
            .||....||:  ||:....: ||:...|.:.|      |..:.  :.|.:....|.:. :|:|.:
  Fly   372 KIYASMHSKD--CLARGSGN-GSVLLTLQIGSEVKENRCGILRAYEMTQEYQRTFISALVVIQNN 433

  Fly   147 LKLITDLGRGYHVRCAYKS---------RDAAMKPKKYLRKHAQKPQAFRSDDRREYGRSLDKQQ 202
            ..:.|...|...|.|...:         ||:::...:.:      |.|...:...||...:
  Fly   434 PNVQTQGDRLIKVGCIQSNATTSLGVSVRDSSVDSSEPV------PSAIALESSLEYTEHM---- 488

  Fly   203 DDDLDEEDVYDANAPTQEEDVTNNEIPMPGCHMKIYNDEHK-IADDVKIGD--PLTIVISIDKQK 264
               ...|.|...|:.|...       |.|...::|.:..|: ..:||:||.  .|.||.....|:
  Fly   489 ---FPHEGVVHYNSSTGPH-------PHPSISLQILDLSHQHETNDVQIGQNLELQIVAEYSPQQ 543

  Fly   265 VY-----------GLHVTDCIVRDGLGWGEQRLVGEDGCPMDNEIMGQFN--YTQDRLAANVTFP 316
            :.           ....|..:.:.........|:.|.|||.|..:.....  :|..|......|.
  Fly   544 LAEHMELQLAPLPDFRATSLVAKTADNENFVLLIDERGCPTDASVFPALERVHTASRSMLRARFH 608

  Fly   317 AHKFPYTTSVYYQCNVRLCALEDPTCQEAPQCSGKRPKRQAAADSKEEDGLPATIEVFSGLYVN- 380
            |.||..|.:|.:...:|.|.   ..|..:...|....:|:..||  :.|..|..:.|.:.:|::
  Fly   609 AFKFSGTANVSFDVKIRFCV---ERCSPSNCISSSWQRRRRQAD--QPDRRPEDLRVQNPVYIST 668

  Fly   381 ------ENENANDSDEDA-------------------VYKEK------TLDDAL-----CVSQRT 409
                  :.:|...|.|:.                   :|.|:      .:||.|     |::| :
  Fly   669 VVDVAPQPDNFTRSQEELPLNYNIRVHGPDQSNTNSYLYGERGVLLIAGIDDPLHLDNVCINQ-S 732

  Fly   410 FAIAIAIAGLILMLAVVAAVLCIMAR 435
            ..||:.|..||..:|::.....::.|
  Fly   733 LLIALFIFWLICQVALLFGCGMVLQR 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pio	NP_001163295.1	ZP	66..349	CDD:214579	68/321 (21%)
pio	NP_001163295.1	Zona_pellucida	<248..349	CDD:278526	25/115 (22%)
CG17111	NP_651119.2	PAN_1	159..255	CDD:278453
CG17111	NP_651119.2	PAN_AP_HGF	270..344	CDD:238532	9/32 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473245
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840