DRSC/TRiP Functional Genomics Resources

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Protein Alignment pio and cutl-6

DIOPT Version :9

Sequence 1:NP_001163295.1 Gene:pio / 37929 FlyBaseID:FBgn0020521 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_492000.2 Gene:cutl-6 / 189075 WormBaseID:WBGene00012165 Length:374 Species:Caenorhabditis elegans


Alignment Length:412 Identity:92/412 - (22%)
Similarity:153/412 - (37%) Gaps:100/412 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 RIKCLSGSMLITIKDAPPNHETGLFSGMIYPKGLSKNSTCLSEYRDHVGSLRYKLPLRSCNTMP- 127
            ::.|....:.:.|..:.|      |.|.|:.||.:|:.:|...|.:: |:..|.|||..|.... 
 Worm    36 KVICAENDLALDIVTSKP------FRGNIFVKGRAKDKSCRQSYANN-GTNSYSLPLGKCGMQRL 93

  Fly   128 KETDDGGIEFFNTIVLQPH-LKLITDLGRGYHVRCAYKSRDAAMKPKKYLRKHAQKPQAFRSDDR 191
            :..:..|:.|..|:::..| ...||...|.:||:|.|      |:|                   
 Worm    94 RSANPRGVNFMVTVIVSFHPAGFITKNDRAFHVKCFY------MEP------------------- 133

  Fly   192 REYGRSLDKQQDDDLDEEDVYDANAPTQEEDVTNNEIPMPGCHMKIYNDEHKIADDVKIGDPLT- 255
                        |::..:::..:..||.|   .::.:.||.|       |:.:..|...|..|| 
 Worm   134 ------------DEIVTQNIDVSMIPTTE---LSDSMVMPKC-------EYSVRRDGPNGPTLTY 176

  Fly   256 -----IVISI------DKQKVYGLHVTDCIVRDGLGWGEQRLVGEDGCPMDNEIMGQFNYTQDRL 309
                 ||..:      |    .|:.|..|.|.||.| .:..:|..|||..|..::.:.:|....:
 Worm   177 ANVGDIVFHVWECTPAD----MGMLVKKCFVTDGDG-EDHAVVDFDGCATDPFLLSELSYDASLM 236

  Fly   310 AANVTFPAHKFPYTTSVYYQCNVRLCALEDPTCQEA--PQCSGKRPKRQAAADSKEEDGLPATIE 372
            .|:.:....|:..:..:|:.|.:|||..:...|||.  |.|..|:...:|:.|            
 Worm   237 RAHASSQVFKYADSNQLYFTCQIRLCQKQMGMCQEVTPPNCGVKKLLSEASGD------------ 289

  Fly   373 VFSGLYVNENENANDSDEDAVYKE-KTLDDA---------LCVSQRTFAIAIAIAGLILMLAVVA 427
               |.......:.:|.:.|....| ..||.|         .||.:....:...|...|:.|.||:
 Worm   290 ---GNRTKREADRSDYEIDVATSELLVLDPADRGLLAPSPFCVPRLLLPVLPLILITIVSLTVVS 351

  Fly   428 AVLCIMARRSTKTVSNSGSSIY 449
            ..|.|..:...|.:....|..|
 Worm   352 TALVIRRQNHKKELDIMQSGRY 373

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pioNP_001163295.1 ZP 66..349 CDD:214579 69/298 (23%)
Zona_pellucida <248..349 CDD:278526 30/114 (26%)
cutl-6NP_492000.2 ZP 38..280 CDD:214579 70/300 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 71 1.000 Domainoid score I6139
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 88 0.386 Inparanoid score I3701
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D376126at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22907
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
66.070

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