Protein Alignment pio and cutl-17

DIOPT Version :9

• Sequence 1: NP_001163295.1
• Gene: pio / 37929
• FlyBaseID: FBgn0020521
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_001379101.1
• Gene: cutl-17 / 185474
• WormBaseID: WBGene00009541
• Length: 912
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 109/539 - (20%)
• Similarity: 178/539 - (33%)
• Gaps: 184/539 - (34%)

  Fly     1 MKTGTRMDAFHTALHLITIAALTTHAAQIPTAMKDAQSSLSDAIAAAEAEVASTSKPAVEPSVRI 65
            :|....:||.|.......|........:|...:.|.....|..|..:..|...||....|..|:.
 Worm   440 LKDNQAVDAVHGVTTTTNIGEKRETKVEIEETVIDDADEFSREIDDSHEESPLTSSEESEGRVKA 504

  Fly    66 K----CLSGSMLITIKDAPPNHETGLFSGMIYPKGLSKNSTCLSEYRDHVGSLRYKLPLRSCNT- 125
            :    |....:.:::|.|.|.      ||.||.|             ||..|.|...    .||
 Worm   505 RLSTECRMSGISVSLKFATPT------SGTIYIK-------------DHFSSCRQSF----SNTS 546

  Fly   126 -----MPKETDD----GGIEF------FNTIVLQPHLK---LITDLGRGYHVRC-----AYKSRD 167
                 :|..|:|    ||||.      :|.:|.:..:|   |:|...:.:.|.|     |.|::.
 Worm   547 FAELHIPFPTEDDSKCGGIESEPHKWDYNVVVERNDMKTPSLVTTKDKTFQVSCDFSKIADKNQL 611

  Fly   168 AAMKPKKYLRKHAQKPQAFRSDDRREYGRSLDKQQDDDLDEEDVYDANAPTQEEDVTNNEIPMPG 232
            ||:|||                                             .|.||.:.::.|
 Worm   612 AALKPK---------------------------------------------VEGDVKSEKVLM-- 629

  Fly   233 CHMKIYNDEHKIADDVKIGDPLTIV-----IS-----IDKQKVYGLHVTDCIVRDGLGWGEQRLV 287
                         :.|:.|..:|.|     :|     ||:....|..:.:||.        :|:.
 Worm   630 -------------EIVRNGQAVTTVPLGAEVSLRWTVIDETDKLGFFINECIA--------ERVG 673

  Fly   288 GE-----------DGCPMD---NEIMGQFNYTQDRLAAN-----VTFPAHKFPYTTSVYYQCNVR 333
            |:           .|||.:   |.::      .|.:..|     ......:|..:..|..:|::.
 Worm   674 GQPPYPEPLKIIYQGCPEEKVRNRLL------HDPVVKNGEVYSTKMKVFRFDGSRRVRIKCSID 732

  Fly   334 LCALEDP--TCQEAP---QCSGKRPKRQAAADSKEEDGLPATIE--------VFSGLYVNENENA 385
            :|..:.|  .|.:..   ..|..|.||    :|..|..|.|..:        |...|.:.:.|..
 Worm   733 VCVEKCPPVICDDLEIRNVDSFGRKKR----NSNVEKWLKAGNKKETRKRRMVTGTLTITDEEET 793

  Fly   386 NDS----DEDAVYKEKTLDDALCVSQRTFAIAIAIAGLILMLAVVAAVL----CIMARRS--TKT 440
            |.:    .|.:.....:.....||.:......|.|..|:::|.:..|:.    |: :|.|  |.:
 Worm   794 NTTVKPRPEFSTSSSSSSQQQYCVQKDRIEFLIVIVVLLILLQIGLALFFYRKCV-SRSSMETSS 857

  Fly   441 VSNSGSSIYSGPYTNTAFS 459
            |.:.|||..|.  |::|::
 Worm   858 VYSEGSSRCSA--TSSAYN 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pio	NP_001163295.1	ZP	66..349	CDD:214579	64/344 (19%)
		Zona_pellucida	<248..349	CDD:278526	24/134 (18%)
cutl-17	NP_001379101.1	PAN_1	26..106	CDD:394981
		PAN_AP_HGF	114..199	CDD:238532
		PAN_AP	208..295	CDD:214680
		PAN_AP_HGF	308..380	CDD:238532
		Zona_pellucida	509..744	CDD:421542	63/331 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910