DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pio and cut-6

DIOPT Version :9

Sequence 1:NP_001163295.1 Gene:pio / 37929 FlyBaseID:FBgn0020521 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_499400.2 Gene:cut-6 / 176520 WormBaseID:WBGene00000853 Length:572 Species:Caenorhabditis elegans


Alignment Length:308 Identity:72/308 - (23%)
Similarity:106/308 - (34%) Gaps:90/308 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 SLRYKLPLRSCNT------MPKETDDGGIEFFNTIVLQPHLKLITDLGRGYHVRCAYKSRDAAMK 171
            |:...:|..:||.      .||     ||....:||...|...:|...:...|:|.|...|    
 Worm   276 SIGLTVPFSACNVHRYRSLNPK-----GIFVEVSIVFMFHSLFMTKTDQTVKVQCFYMEAD---- 331

  Fly   172 PKKYLRKHAQKPQAFRSDDRREYGRSLDKQQDDDLDEEDVYDANAPTQEEDVTNNEIPMPGCHMK 236
                  ||...|              |.......:..|.:|.                ||.|...
 Worm   332 ------KHVTVP--------------LSVSMITTVFREQIYQ----------------MPQCAYT 360

  Fly   237 IYNDEHKIADDVKIGDPLTIVISI------------DKQKVYGLHVTDCIVRDGLGWGEQRLVGE 289
            :    .|.|.|..|....|:..|:            ||. .:|:.|..|.|.:|.| ....::..
 Worm   361 L----RKGAPDGPIVRFATLGESVYHRWECIEVEGADKD-TFGMLVHSCYVDNGYG-DRVDILDS 419

  Fly   290 DGCPMDNEIMGQFNY-TQDRLAANVTFPAHKFPYTTS--VYYQCNVRLCALEDPTCQ--EAPQCS 349
            :||.:|..::...:| |..|||   |.|.|.|.|...  :.:||.:.||...|..|:  ..||..
 Worm   420 NGCGLDAVLLSTPDYDTSLRLA---TKPYHVFKYADRPVLQFQCQITLCLKYDGGCEGITPPQNC 481

  Fly   350 GK-----------RPKRQAAADSKEEDGLPATIEVFS-GLYVNENENA 385
            .|           .|:::.....:..||: .||:||: .:.|.|.|.|
 Worm   482 KKLPGEDGHHHHHHPEKRRKLVRRLADGV-GTIDVFTDSVTVLEQEPA 528

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pioNP_001163295.1 ZP 66..349 CDD:214579 60/258 (23%)
Zona_pellucida <248..349 CDD:278526 32/117 (27%)
cut-6NP_499400.2 VWA 48..208 CDD:395045
ZP 233..480 CDD:214579 59/257 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 71 1.000 Domainoid score I6139
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 88 0.386 Inparanoid score I3701
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D877658at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22907
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
66.070

Return to query results.
Submit another query.