DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4681 and Tex9

DIOPT Version :9

Sequence 1:	NP_611937.2	Gene:	CG4681 / 37928	FlyBaseID:	FBgn0069913	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	XP_002729984.1	Gene:	Tex9 / 300822	RGDID:	1304772	Length:	431	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	97/407 - (23%)
Similarity:	180/407 - (44%)	Gaps:	69/407 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ELLSREKELFKINQELNLLTLSPAADAMYPAKGSSKSTAVAVPRFATFQKQK---GPSSLLRKKG 64
            :||:||:|..::|.||...|.:....|....:...:..|.......|..|::   ||..||..:|
  Rat    70 DLLAREQEYKRLNAELEAKTANLVRQAEEVIREQQEERARPFSALTTSCKEEDGYGPRDLLSSEG 134

  Fly    65 APTACTKAAPKASPGRETVPTARSPMPDMSLLTKSKPAAGPTSPTPRNLSKFSTFTKDVSSKTAT 129
                      .|.|..||.|..::              .||.:.....|     .:.|...|..:
  Rat   135 ----------MAHPWSETKPKTKN--------------TGPVNKIQNRL-----HSADKERKINS 170

  Fly   130 YVKYRNPNFSESPSLDELLRNDADEANRKPDVVEVEVTQKRESTTVVNGQLKKQV-----TKDNF 189
            .||.:.|:...:.  |..:.:|..:.:....:..:|            |||::.|     ..|:|
  Rat   171 SVKLKYPDVQTAN--DVAIPDDFSDFSLAKTISRIE------------GQLEEDVLPECADDDSF 221

  Fly   190 ------------IKFLKAKVAILEEDHAQHAGELIRQKEQLEHALEAQRKSEHQRDQAINSNKHL 242
                        |:|||||:.:::|:......|..:::::::   :.:.|.::..:..:...:.:
  Rat   222 CGVSKDIGTEAQIRFLKAKLHVMQEELDSVVCECNKKEDEIQ---DLKSKVKNLEEDCVRQQRTV 283

  Fly   243 SEQLMRSERQ---CEGFNQRQKEQQLEFITQQRELEVLKRDAKVSRQTNINLENRLSRVQEDADA 304
            :.|..:.|:.   .|..|:|..|.|.:..:..||||..:|..|.:..:....|.||:|..|:|:.
  Rat   284 TSQQTQIEKYRNLFEEANKRCDELQQQLSSVDRELENKRRLQKQAATSQSATEVRLNRALEEAEK 348

  Fly   305 ARQELKLLREEQRDQLEAHRKELKLRDSRIRALKRQRGDLLNAYKKQLYMIDNLKRQTICLEQSA 369
            .:.||..||:..:|......:::::..|..:.|:||:|:|:..:||||.:||.||||.:.:|.:.
  Rat   349 YKAELSKLRQTNKDITNEDHQKIEVLKSENKKLERQKGELMIGFKKQLKLIDILKRQKMHIEAAK 413

  Fly   370 AIGFGEKEFNKVLDWNA 386
            .:.|.|:||.|.|:|.:
  Rat   414 MLSFSEEEFMKALEWGS 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4681	NP_611937.2	SMC_prok_B	<146..>347	CDD:274008	47/220 (21%)
Tex9	XP_002729984.1	Smc	<231..427	CDD:224117	55/198 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338062
Domainoid	1	1.000	102	1.000	Domainoid score	I6661
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4865
OMA	1	1.010	-	-		QHG50184
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008332
OrthoInspector	1	1.000	-	-		oto97959
orthoMCL	1	0.900	-	-		OOG6_104916
Panther	1	1.100	-	-	LDO	PTHR23313
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.900