DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Start1 and Stard3nl

DIOPT Version :9

Sequence 1:	NP_001246495.1	Gene:	Start1 / 37927	FlyBaseID:	FBgn0035028	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001008299.1	Gene:	Stard3nl / 291182	RGDID:	1308633	Length:	235	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	93/249 - (37%)
Similarity:	137/249 - (55%)	Gaps:	42/249 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PSDVRSTAQLILANARQGNSAYNMQYDMSRAHSIN---LITEDFLAGYMQDGR----MSVVRRFF 63
            |.|:.:|    |..::..:::      :...||||   |:..  :..|  :||    :|.|||.|
  Rat     5 PEDMENT----LTGSQSSHAS------LRDIHSINPGQLMAR--IESY--EGREKKGISDVRRTF 55

  Fly    64 CLFVTFDLVFVSLLWLICIVINGDNIFTAFHKQIVEYTIYKSLFDVVAVAICRFLVLIFFYAILY 128
            ||||||||:||:|||:|.:.:|| .|.....|::..|..|.|.||:..:|:.||.|||..||:..
  Rat    56 CLFVTFDLLFVTLLWIIELNVNG-GIENTLKKEVAHYDYYSSYFDIFLLAVFRFKVLILGYAVCR 119

  Fly   129 INHWSIIALSTSGSCLFLISKVFVFDWLDSK---QQVFEVILIITSFILAWGEAWFLDCRVIPQE 190
            :.||..|||:|:.:..||::||.:     ||   |..|..:|.|.||||||.|.||||.:|:|||
  Rat   120 LRHWWAIALTTAVTSAFLLAKVIL-----SKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQE 179

  Fly   191 RHAQHYFRTMTSNDRTPMEQPAILIEQERPPQSVTD--FYSLMDTARHSDEEDE 242
              |:...|.:...|.:  |:.|::      |..::|  |||..::...|:||.|
  Rat   180 --AEEENRLLLVQDAS--ERAALI------PAGLSDGQFYSPPESEAGSEEEAE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Start1	NP_001246495.1	MENTAL	57..232	CDD:287435	77/179 (43%)
Start1	NP_001246495.1	SRPBCC	247..571	CDD:301327
Stard3nl	NP_001008299.1	MENTAL	49..212	CDD:402197	77/178 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335625
Domainoid	1	1.000	123	1.000	Domainoid score	I5457
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I3963
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437203at2759
OrthoFinder	1	1.000	-	-		FOG0001150
OrthoInspector	1	1.000	-	-		otm45043
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46121
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.000