DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and CPR3

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_013633.1	Gene:	CPR3 / 854897	SGDID:	S000004543	Length:	182	Species:	Saccharomyces cerevisiae

Alignment Length:	159	Identity:	78/159 - (49%)
Similarity:	97/159 - (61%)	Gaps:	10/159 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 QRIYENVVLHTTK-GDIHMRLFFKEVPKTVENF---CVHAKNGYYNGHIFHRVIKGFMVQTGDPT 538
            ::::.:..::.|| |.|...|:...||||.|||   |...|...|.|..|||:|..||:|.||..
Yeast    22 KKVFFDPAVNGTKIGRIEFELYDNVVPKTAENFRALCTGEKGWGYKGVPFHRIIPDFMIQGGDTD 86

  Fly   539 GT-GTGGKSIWGSDFKDE-FVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGR 601
            .| |.|||||:||.|.|| ||.  |||:...:|||||||||||||||||.:|.||||.||.|||.
Yeast    87 LTNGFGGKSIYGSKFADENFVK--KHDKAGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGE 149

  Fly   602 VYRGMEVVLNICNSKANPKTDKPYDDIKI 630
            |.:||::|..|  ......:.||..:|.|
Yeast   150 VTKGMDIVKAI--ESYGTASGKPRAEIVI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	78/152 (51%)
CPR3	NP_013633.1	cyclophilin_ABH_like	23..180	CDD:238907	78/158 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840