DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and PPIL3

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_115861.1	Gene:	PPIL3 / 53938	HGNCID:	9262	Length:	165	Species:	Homo sapiens

Alignment Length:	174	Identity:	71/174 - (40%)
Similarity:	88/174 - (50%)	Gaps:	38/174 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 NVVLHTTKGDIHMRLFFKEVPKT--VENFCVHAKNGYYNGHIFHRVIKGFMVQTGD-------PT 538
            :|.|||..|||.:.:|.:..|||  :|:.||....                ||..|       |.
Human     2 SVTLHTDVGDIKIEVFCERTPKTCEMESRCVPQAG----------------VQWRDLGSLQPPPP 50

  Fly   539 G-----------TGTGGKSIWGSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWL 592
            |           ||.||.||||..|:||:...|||:....|||||.||||||||||||....|.|
Human    51 GFKQVFCLSLPRTGRGGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHL 115

  Fly   593 DNKHTVFGRVYRGMEVVLNICNSKANPKTDKPYDD--IKIISIH 634
            |.|:||||:|..|:|.:..:.....|.||.:|.:|  ||.|:||
Human   116 DMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITIH 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	68/169 (40%)
PPIL3	NP_115861.1	cyclophilin	1..158	CDD:294131	69/171 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920