DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and Moca-cyp

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_733246.1	Gene:	Moca-cyp / 43374	FlyBaseID:	FBgn0039581	Length:	970	Species:	Drosophila melanogaster

Alignment Length:	152	Identity:	73/152 - (48%)
Similarity:	86/152 - (56%)	Gaps:	14/152 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 GDIHMRLFFKEVPKTVENF---C--------VHAKNGYYNGHIFHRVIKGFMVQTGD-PTGTGTG 543
            |.|...||....|||.|||   |        :..|...|.|.|||||:|.||||.|| ..|.|||
  Fly    27 GRIVFELFNDVAPKTAENFRALCTGEKGFGLITGKKLQYKGVIFHRVVKDFMVQAGDFSAGNGTG 91

  Fly   544 GKSIWGSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYRGMEV 608
            |:||:|..|:||.... |||||:.:||||.|.||||||||||..|.|.|||.|.|||:|..|.|:
  Fly    92 GESIYGGTFEDESFEK-KHDRPFLLSMANRGKNTNGSQFFITTQPAPHLDNIHVVFGQVISGQEL 155

  Fly   609 VLNICNSKANPKTDKPYDDIKI 630
            |..:.....: :..:|..|..|
  Fly   156 VRQLEGLPVD-RNSRPLQDAAI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	73/152 (48%)
Moca-cyp	NP_733246.1	cyclophilin	13..180	CDD:294131	73/152 (48%)
Moca-cyp	NP_733246.1	SH3-RhoG_link	635..>718	CDD:293215
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447241
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840