DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and CG5808

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_651291.1	Gene:	CG5808 / 42957	FlyBaseID:	FBgn0027617	Length:	653	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	64/158 - (40%)
Similarity:	88/158 - (55%)	Gaps:	13/158 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 NVVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSI 547
            :||:.||.||:.:.||..|.|....||....:..|||.::||.|.:||:.|||||:|.|.||.||
  Fly     2 SVVIETTMGDLTVDLFISERPIACLNFLKLCRLKYYNFNLFHTVQQGFIAQTGDPSGAGDGGSSI 66

  Fly   548 WG-------SDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITV---LPTPWLDNKHTVFGRV 602
            ||       ..|:.||:|.:.|.....:|:.:||.|..|||||:|:   |.:  ||..|.|.|.|
  Fly    67 WGVVEGPQKRFFEAEFLPKINHSSAGMLSLVSAGKNLVGSQFFLTLGENLTS--LDGNHCVIGEV 129

  Fly   603 YRGMEVVLNICNSKANPKTDKPYDDIKI 630
            ..|.||:..: |......:.:||.||:|
  Fly   130 VEGHEVLRKL-NDAIVDDSFRPYQDIRI 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	63/156 (40%)
CG5808	NP_651291.1	cyclophilin_RRM	4..169	CDD:238902	63/156 (40%)
		RRM	<237..445	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447236
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840