DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and cwc27

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_957397.1	Gene:	cwc27 / 394078	ZFINID:	ZDB-GENE-040426-1118	Length:	470	Species:	Danio rerio

Alignment Length:	160	Identity:	74/160 - (46%)
Similarity:	97/160 - (60%)	Gaps:	15/160 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 VVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSIW 548
            |:|.|:.|||.:.|:.||.||...||......|||:|.||||::..|:||.||||||||||:||:
Zfish    15 VLLKTSAGDIDIELWSKETPKACRNFVQLCMEGYYDGTIFHRMVPEFIVQGGDPTGTGTGGESIY 79

  Fly   549 GSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGR-----VYRGMEV 608
            |..|||||...|:.:|...|:||||||:.||||||.|:.....|:||||:||:     ||..:.:
Zfish    80 GRPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVYNMLRL 144

  Fly   609 VLNICNSKANP-------KTD---KPYDDI 628
            ....|:....|       .|:   .|:|||
Zfish   145 ADVACDGDERPLNPHKIRSTEVLHSPFDDI 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	73/159 (46%)
cwc27	NP_957397.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	74/160 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	172..377		3/3 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920