DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and ppil2

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_957285.2	Gene:	ppil2 / 393966	ZFINID:	ZDB-GENE-040426-1096	Length:	524	Species:	Danio rerio

Alignment Length:	149	Identity:	84/149 - (56%)
Similarity:	106/149 - (71%)	Gaps:	0/149 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 VVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSIW 548
            |.|||.|||:::.|...:|||..|||....|.|||:|.:|||.|:.||:|.||||||||||:|.|
Zfish   282 VRLHTNKGDLNVELHCDKVPKAGENFIKLCKKGYYDGTVFHRSIRNFMIQGGDPTGTGTGGESFW 346

  Fly   549 GSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYRGMEVVLNIC 613
            |..|||||.|:|.|.....:||||:|||||.||||||.....:||.||:|||||..|:|.:..:.
Zfish   347 GKPFKDEFRPNLSHTGRGILSMANSGPNTNKSQFFITFRSCAYLDRKHSVFGRVVGGLETLSAME 411

  Fly   614 NSKANPKTDKPYDDIKIIS 632
            |.:::||||||..:|||:|
Zfish   412 NVESDPKTDKPKSEIKILS 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	83/148 (56%)
ppil2	NP_957285.2	Ubox	42..96	CDD:128780
ppil2	NP_957285.2	cyclophilin_RING	281..440	CDD:238904	84/149 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920