DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and CG11777

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_724939.1	Gene:	CG11777 / 36108	FlyBaseID:	FBgn0033527	Length:	161	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	76/154 - (49%)
Similarity:	95/154 - (61%)	Gaps:	2/154 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 NVVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSI 547
            :|.|||..||:.:.||....||..|||.....:.||:|.:|.|.||||:|||||||.||..|:||
  Fly     2 SVTLHTDVGDLKIELFCDACPKACENFLALCASDYYSGCVFIRNIKGFIVQTGDPTNTGKNGQSI 66

  Fly   548 WGSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYRGMEVVLNI 612
            ||..|.|||..::||.....|||||.|||.|.||||||....|.||.|:|:||||..|.:.:..:
  Fly    67 WGQKFDDEFKETIKHTDRGMVSMANNGPNANASQFFITYAAQPNLDLKYTLFGRVIDGFDALDEL 131

  Fly   613 CNSKANPKTDKPYDDIKI--ISIH 634
            .....|||..:|:.|.||  ::||
  Fly   132 EKLPVNPKNYRPHVDKKINGVTIH 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	73/149 (49%)
CG11777	NP_724939.1	Cyclophilin_PPIL3_like	1..154	CDD:238909	74/151 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447210
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45625
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950