Protein Alignment CG3511 and PPIL6

DIOPT Version :10

• Sequence 1: NP_611935.1
• Gene: CG3511 / 37926
• FlyBaseID: FBgn0035027
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001104768.2
• Gene: PPIL6 / 285755
• HGNCID: 21557
• Length: 337
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 82/312 - (26%)
• Similarity: 124/312 - (39%)
• Gaps: 116/312 - (37%)

  Fly   391 RPLQVAL--------FQGRIKRQKAAITMEQEASENPALQNILNDPTAF----CTAYKKSRFYLY 443
            |||||.:        ||           :.:.|:||  |:|  |.|:.|    ....::..::.|
Human    22 RPLQVKVVGLFSCPNFQ-----------IAKSAAEN--LKN--NHPSKFEDPILVPLQEFAWHQY 71

  Fly   444 SRRLPSDLQDVDRDIFNE------------------------KPSKE--DIIAVPEASVVQRIYE 482
                   ||:..|::.||                        |.:.|  ||:.:..:::...:.|
Human    72 -------LQEKKRELKNETWEYSSSVISFVNGQFLGDALDLQKWAHEVWDIVDIKPSALYDALTE 129

  Fly   483 NV---VLHTTKGDIHM-----------RLFFK----EVPKTVENFCV--HAKNGY--------YN 519
            :.   .|..||.|...           ||.|:    ..|||.:||.|  ..|.|:        |.
Human   130 DFSAKFLRDTKHDFVFLDICIDSSPIGRLIFELYCDVCPKTCKNFQVLCTGKAGFSQRGIRLHYK 194

  Fly   520 GHIFHRVIKGFMVQTGDPT-GTGTGGKSIWGSDFKDEFVPSLK---------------------- 561
            ..||||:::...:|.||.. |.|..|:||:|..| :|...|||
Human   195 NSIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTF-EELYGSLKRSVKRQKESRGVGKIEKYRDEN 258

  Fly   562 ----HDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYRGMEVV 609
                |::...:.|||.|.::|||||:||:..||:||.|...||::..|.||:
Human   259 FSVPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_611935.1	WD40 repeat	85..122	CDD:293791
		WD40	<94..310	CDD:441893
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	56/177 (32%)
PPIL6	NP_001104768.2	cyclophilin	144..333	CDD:469651	52/168 (31%)