DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3511 and cyn-12

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_501118.1	Gene:	cyn-12 / 191627	WormBaseID:	WBGene00000888	Length:	169	Species:	Caenorhabditis elegans

Alignment Length:	153	Identity:	80/153 - (52%)
Similarity:	101/153 - (66%)	Gaps:	1/153 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 VVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSIW 548
            |:|.||.|.|.:.|::...|:|.:||...||..||||.||||:|..||:|.|||||||.||.||:
Worm    12 VILDTTMGKIALELYWNHAPRTCQNFSQLAKRNYYNGTIFHRIIADFMIQGGDPTGTGRGGASIY 76

  Fly   549 GSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYRGMEVVLNIC 613
            |..|.||....|||.....:|||||||||||||||||:.||..||.|||:||||..||:|:.|:.
Worm    77 GDKFSDEIDERLKHTGAGILSMANAGPNTNGSQFFITLAPTQHLDGKHTIFGRVAAGMKVIANMG 141

  Fly   614 NSKANPKTDKPYDDIKIISIHLS 636
            ....: ..|:|..:|:|:..:.|
Worm   142 RVDTD-NHDRPKIEIRILKAYPS 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	78/147 (53%)
cyn-12	NP_501118.1	cyclophilin_SpCYP2_like	13..159	CDD:238903	78/146 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920