DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3511 and cyn-4

DIOPT Version :9

Sequence 1:	NP_001286847.1	Gene:	CG3511 / 37926	FlyBaseID:	FBgn0035027	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	91/238 - (38%)
Similarity:	121/238 - (50%)	Gaps:	42/238 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 AYKKSRFYLYSRRL----PSDLQDVDRDIFNEKPSKE-----------------------DIIAV 471
            |.|..:||:  ||:    .|.|..:|::...:|.|.|                       ..:..
Worm   194 AMKDPKFYI--RRMNNACKSVLDQLDKEYVPKKSSTETDETADEINAAHYSQGKVAAGFTSTVMA 256

  Fly   472 P----EASVV-------QRIYEN--VVLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIF 523
            |    :|:|:       .|:.:|  |.|.|..|.:::.||..:|||..|||..|..|||||...|
Worm   257 PVTSNKAAVLDNDTVRYSRVKKNAFVRLVTNFGPLNLELFAPKVPKACENFITHCSNGYYNNTKF 321

  Fly   524 HRVIKGFMVQTGDPTGTGTGGKSIWGSDFKDEFVPSLKHDRPYTVSMANAGPNTNGSQFFITVLP 588
            ||:||.||:|.|||||||.||:|||...|.|||:....||....:||||.|.||||||||||..|
Worm   322 HRLIKNFMLQGGDPTGTGHGGESIWDKPFSDEFISGFSHDARGVLSMANKGSNTNGSQFFITFRP 386

  Fly   589 TPWLDNKHTVFGRVYRGMEVVLNICNSKANPKTDKPYDDIKII 631
            ..:||.|||:|||:..|.:.:..|...:....||.|...:.|:
Worm   387 CKYLDRKHTIFGRLVGGQDTLTTIEKLETEEGTDVPMVSVVIM 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3511	NP_001286847.1	WD40	<75..>312	CDD:225201
		WD40	<79..300	CDD:295369
		WD40 repeat	85..122	CDD:293791
		WD40 repeat	128..176	CDD:293791
		WD40 repeat	181..210	CDD:293791
		WD40 repeat	218..268	CDD:293791
		WD40 repeat	275..311	CDD:293791
		cyclophilin_WD40	485..633	CDD:238908	73/147 (50%)
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	74/149 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920