DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fcp1 and TIM50

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_015262.1	Gene:	TIM50 / 856042	SGDID:	S000005984	Length:	476	Species:	Saccharomyces cerevisiae

Alignment Length:	220	Identity:	52/220 - (23%)
Similarity:	80/220 - (36%)	Gaps:	63/220 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 RKLVLLVDLDQTVIHTTNDTVPDNIKGIYHFQLYGPHSPW-----YHTRLRPGTAEFLERMSQLY 265
            |.|.|::.|:..::                      ||.|     :.|..|||...||..:||.|
Yeast   190 RPLTLVITLEDFLV----------------------HSEWSQKHGWRTAKRPGADYFLGYLSQYY 232

  Fly   266 ELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDECFNATSKTDNLKALFPNGD-SMVCIIDDR 329
            |:.:.:.....|:..||:.|||...|.|:.:......:.......:|..|  |.| |.|.|||..
Yeast   233 EIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKL--NRDLSKVIIIDTD 295

  Fly   330 EDVWNM-ASNLIQVKP-----------------YHFFQHTGDINAPPGLSKHELDGEGVDFKEIT 376
            .:.:.: ..|.|.::|                 |...|.|.|:.  |.|:..|      |.|.:.
Yeast   296 PNSYKLQPENAIPMEPWNGEADDKLVRLIPFLEYLATQQTKDVR--PILNSFE------DKKNLA 352

  Fly   377 EKHGDKDKTESSSEVKPEDTDKGDN 401
            |:...:.|       |.:|...||:
Yeast   353 EEFDHRVK-------KLKDKFYGDH 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	38/165 (23%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
TIM50	NP_015262.1	FCP1	1..354	CDD:227517	46/195 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900