DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and PSR2

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_013119.1	Gene:	PSR2 / 850706	SGDID:	S000004009	Length:	397	Species:	Saccharomyces cerevisiae

Alignment Length:	343	Identity:	73/343 - (21%)
Similarity:	114/343 - (33%)	Gaps:	102/343 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NIPDEEGATPSRAPGG---------VAASGAAEGDDGGGGSGAKNSASGN----------SNNNT 48
            |....:|......|.|         :..|.:..|.:.|..:..:|..|||          |||
Yeast    39 NKAQTQGRKQKATPNGDKMQYSTPEILLSSSDSGSNAGSKTMQENGNSGNGKLAPLSRDHSNN-- 101

  Fly    49 SGGGIIVLRAALGENEARAVINKWRVREGQFVSAAQILFLYQPVGVDAKDAKDAGKPGGDCAIQR 113
                      :..|.:.....|:..|...:..:|.           :.::..|..|...|..:..
Yeast   102 ----------SYDEEKEYEDYNEGDVEMTEVNNAG-----------EEEEEDDEAKEKQDHVVHE 145

  Fly   114 YK--SQRAGVVKKRLRKEGELLTKGDAILELSECIHTTVIKDMCADCGADLRQNENG---QTSEA 173
            |.  :.|...:......:..|...|.              :||.....|....|:..   .|.|.
Yeast   146 YNVDADRNSSINDEAPPQQGLYQVGQ--------------EDMNPQYVASSPDNDLNLIPTTEED 196

  Fly   174 SVPMVHTMPDLKVTQKLAQKLGHDDTRRLLA------DRKLVLLVDLDQTVIHTTND-------- 224
            ...:.|..||    |..|.  |:|   .||.      .:|..|::|||:|::|::..
Yeast   197 FSDLTHLQPD----QYHAP--GYD---TLLPPKLQEFQQKKCLILDLDETLVHSSFKYMHSADFV 252

  Fly   225 ---TVPDNIKGIYHFQLYGPHSPWYHTRLRPGTAEFLERMSQLYELHICTFGARNYAHMIAQLLD 286
               .:.|.:..:|..:             |||..|||.|:|||||:.:.|.....||:.:...||
Yeast   253 LPVEIDDQVHNVYVIK-------------RPGVDEFLNRVSQLYEVVVFTASVSRYANPLLDTLD 304

  Fly   287 PEGKFFSHRILSRDECFN 304
            |.|..  |..|.|:.|:|
Yeast   305 PNGTI--HHRLFREACYN 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	11/84 (13%)
		FCP1_euk	202..348	CDD:131304	35/120 (29%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
PSR2	NP_013119.1	FCP1	5..397	CDD:227517	73/343 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810