DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and Timm50

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_079892.1	Gene:	Timm50 / 66525	MGIID:	1913775	Length:	353	Species:	Mus musculus

Alignment Length:	150	Identity:	33/150 - (22%)
Similarity:	66/150 - (44%)	Gaps:	20/150 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 DLDQTVIHTTND-TVPDNIKGIYH-------FQLYGP--HSPW-----YHTRLRPGTAEFLERMS 262
            |..|.:|..|:. .:||.::..|:       .:|.|.  |..|     :..:.|||.....::::
Mouse   121 DYRQMIIEPTSPCLLPDPLREPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLA 185

  Fly   263 QLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDECFNATSKTDNLKALFPNGD-SMVCII 326
            .|||:.|.|......|..:...:||.| |.|:|:......:.......::..|  |.| :.|.::
Mouse   186 PLYEIVIFTSETGMTAFPLIDSVDPHG-FISYRLFRDATRYMEGHHVKDISCL--NRDPARVVVV 247

  Fly   327 DDREDVWNMAS-NLIQVKPY 345
            |.:::.:.:.. |.:.::|:
Mouse   248 DCKKEAFRLQPFNGVALRPW 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	33/149 (22%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
Timm50	NP_079892.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..59
Timm50	NP_079892.1	NIF	148..295	CDD:281081	26/122 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900