DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and CTDSP1

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	XP_016860104.1	Gene:	CTDSP1 / 58190	HGNCID:	21614	Length:	409	Species:	Homo sapiens

Alignment Length:	262	Identity:	68/262 - (25%)
Similarity:	109/262 - (41%)	Gaps:	61/262 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LFLYQPVGVDAKDA--KDAGKPGGDCAIQ---RYKSQRAGVVKKRLRKEGELLTKGDAILELSEC 145
            :|.:.|.|....||  :.|....|..|.:   |:|..:.....::.|..|        ||....|
Human   121 VFSFSPCGPQDLDAAPRSAHPRLGLAAPELRARWKGDQKSAASQKPRSRG--------ILHSLFC 177

  Fly   146 IHTTVIKD----MCADCGADLRQNENGQTSEASVPMVHTMPDLKVTQKLAQKLGHDDTRRLLADR 206
               .|.:|    :.|..||.|...|||...: ..|:.:.:|:.|...                ..
Human   178 ---CVCRDDGEALPAHSGAPLLVEENGAIPK-QTPVQYLLPEAKAQD----------------SD 222

  Fly   207 KLVLLVDLDQTVIHTT----NDT---VPDNIKGIYHFQLYGPHSPWYHTRLRPGTAEFLERMSQL 264
            |:.:::|||:|::|::    |:.   :|..|.|:.| |:|        ...||...|||:||.:|
Human   223 KICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVH-QVY--------VLKRPHVDEFLQRMGEL 278

  Fly   265 YELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDEC-FNATSKTDNLKALFPNGDSM--VCII 326
            :|..:.|.....||..:|.|||..|.|.:.  |.|:.| |:..:...:|..|   |..:  |.|:
Human   279 FECVLFTASLAKYADPVADLLDKWGAFRAR--LFRESCVFHRGNYVKDLSRL---GRDLRRVLIL 338

  Fly   327 DD 328
            |:
Human   339 DN 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	14/60 (23%)
		FCP1_euk	202..348	CDD:131304	41/137 (30%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
CTDSP1	XP_016860104.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810