DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and ctdspl3

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	XP_021335375.1	Gene:	ctdspl3 / 571337	ZFINID:	ZDB-GENE-141215-56	Length:	360	Species:	Danio rerio

Alignment Length:	158	Identity:	48/158 - (30%)
Similarity:	75/158 - (47%)	Gaps:	31/158 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 LLVDLDQTVIHTTNDTVPDNIKGIYHFQL-YGPHSPWYHTRLRPGTAEFLERMSQLYELHICTFG 273
            |::|||:|::.::.:.:||   ..|.|.. :..|....:..|||...|||:.|::.:|:.:.|..
Zfish   184 LVLDLDETLVFSSLNVIPD---AEYTFNTRFQDHKYKVYVILRPHVREFLQAMTKHFEMFVYTSA 245

  Fly   274 ARNYAHMIAQLLDPEGKFFSHRILSRDECF--------------NATSKT---DNLKALFP-NGD 320
            .:.||..|..:|||..|.|.|| |.:|:|.              ...|||   ||....|| :..
Zfish   246 KKEYAEKIVDILDPNKKLFRHR-LYQDDCACVLGHYIKDLTILERDLSKTVILDNAPHTFPYHLM 309

  Fly   321 SMVCI---IDDREDVWNMASNLIQVKPY 345
            :|:.|   |.|:||     ..|.::.||
Zfish   310 NMIPIKSWIGDQED-----RELQKLIPY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	48/158 (30%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
ctdspl3	XP_021335375.1	Atrophin-1	<19..182	CDD:331285
ctdspl3	XP_021335375.1	NIF	183..343	CDD:308590	48/158 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810