DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and ctdsp1

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	XP_021334687.1	Gene:	ctdsp1 / 553744	ZFINID:	ZDB-GENE-050522-523	Length:	1222	Species:	Danio rerio

Alignment Length:	443	Identity:	98/443 - (22%)
Similarity:	154/443 - (34%)	Gaps:	152/443 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 AAEGDDGGGGSGAK-------------------NSASGN-SNNNTSGGGIIVLRAALG------- 61
            :..||..|..:|.|                   |.|:.| :|.:.:.|.:..||:|..
Zfish   808 SVSGDSTGLCAGEKTFQAADSSDSPDEESTLLENLANQNLTNRSENEGSVQDLRSADEIDVNGEF 872

  Fly    62 ----ENEAR--AVINKWRVREGQFVSAAQILFLYQPVGVDAKDAKDAGK--PGGD----CAIQRY 114
                |||..  ....:....|.:..|    ||.::.: |...|..|.|:  |..|    |.|:..
Zfish   873 CPDFENEGAHGPCCGEIETSEDEETS----LFGFEDL-VGCSDESDDGEVIPTNDPQLSCTIEEL 932

  Fly   115 KSQRAGV--VKKRLRKE----GELL-----------TKGDAILELSECIHTTV---IKDMCADCG 159
            .:.....  |...|..|    .|||           ||.:..||  |.||...   ..:..|.|.
Zfish   933 SNTETSTPCVSDSLDTEPKDTSELLNSPAVGGLAEQTKPNEKLE--ELIHQVARSEASEQEAICK 995

  Fly   160 ADLRQN-------ENGQTSE-----------------ASVPMVHTMPDLKVTQKLAQKLGHDDTR 200
            :|.::.       |:.::||                 ..||....:|.:|     ::.:|
Zfish   996 SDQKKTGEQCDSYEDSESSEDEEFSEDCDCEICVPPTDQVPAKPLLPQIK-----SKDVG----- 1050

  Fly   201 RLLADRKLVLLVDLDQTVIHTT----NDT---VPDNIKGIYHFQLYGPHSPWYHTRLRPGTAEFL 258
                  |:.:::|||:|::|::    |:.   :|..|.|..| |:|        ...||...|||
Zfish  1051 ------KICVVIDLDETLVHSSFKPVNNADFIIPVEIDGTVH-QVY--------VLKRPHVDEFL 1100

  Fly   259 ERMSQLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDEC-----------------FNAT 306
            :||.:|:|..:.|.....||..::.|||..|.|.|.  |.|:.|                 .|..
Zfish  1101 KRMGELFECVLFTASLAKYADPVSDLLDKWGAFRSR--LFRESCVFHRGNYVKDLSRLGRDLNKV 1163

  Fly   307 SKTDNLKALF----PNGDSMVCIIDDREDVWNMASNLIQVKPYHFFQHTGDIN 355
            ...||..|.:    .|...:....||..|     :.|:.:.|  ||:....::
Zfish  1164 IIVDNSPASYIFHPDNAVPVASWFDDMSD-----TELLDLIP--FFERLSKVD 1209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	25/118 (21%)
		FCP1_euk	202..348	CDD:131304	44/173 (25%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
ctdsp1	XP_021334687.1	HIF-SF_euk	1051..1209	CDD:274055	46/175 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810