DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and CTDSPL2

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_057480.2	Gene:	CTDSPL2 / 51496	HGNCID:	26936	Length:	466	Species:	Homo sapiens

Alignment Length:	164	Identity:	48/164 - (29%)
Similarity:	75/164 - (45%)	Gaps:	43/164 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 LLVDLDQTVIH-TTND------TVPDNIKGIYHFQLYGPHSPWYHTRLRPGTAEFLERMSQLYEL 267
            |::|||:|::| :.|:      |.|...:.:. :|:|        .||||...||||||||:||:
Human   290 LVLDLDETLVHCSLNELEDAALTFPVLFQDVI-YQVY--------VRLRPFFREFLERMSQMYEI 345

  Fly   268 HICTFGARNYAHMIAQLLDPEGKFFSHRILSRDECF--------------NATSKT---DNLKAL 315
            .:.|...:.||..:..:|||:.:...|| |.|:.|.              ...|||   ||....
Human   346 ILFTASKKVYADKLLNILDPKKQLVRHR-LFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQA 409

  Fly   316 F----PNGDSMVCIIDDREDVWNMASNLIQVKPY 345
            |    .||..:.....|:.|     :.|:::.|:
Human   410 FAYQLSNGIPIESWFMDKND-----NELLKLIPF 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	48/164 (29%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
CTDSPL2	NP_057480.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..140
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..240
		HIF-SF_euk	287..448	CDD:274055	48/164 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810