DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and ctdnep1b

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_001007441.2	Gene:	ctdnep1b / 492799	ZFINID:	ZDB-GENE-041114-152	Length:	248	Species:	Danio rerio

Alignment Length:	175	Identity:	48/175 - (27%)
Similarity:	76/175 - (43%)	Gaps:	23/175 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 RLLADRKLVLLVDLDQTVIHTTND----------TVPDNIKGIYHFQLYGPHSPWYHTRLRPGTA 255
            ||...::.:|::|||:|:||:.:|          |.||.|..:    :...|...:....||...
Zfish    59 RLNNVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKV----VIDKHPVRFFVHKRPHVD 119

  Fly   256 EFLERMSQLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDEC-FNATSKTDNLKALFPNG 319
            .|||.:||.|||.:.|.....|...:|..|| ..|....|...|..| .::.|...:|..:..:.
Zfish   120 FFLEVVSQWYELVVFTASMEIYGSAVADKLD-NNKAILKRRYYRQHCTLDSGSYIKDLSVVHDDL 183

  Fly   320 DSMVCIIDDREDVW-NMASNLIQVKPYHFFQHTGD---INAPPGL 360
            .|:| |:|:....: :...|.|.:|.:  |....|   :|..|.|
Zfish   184 SSVV-ILDNSPGAYRSHPDNAIPIKSW--FSDPSDTALLNLLPML 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	42/157 (27%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
ctdnep1b	NP_001007441.2	HIF-SF_euk	65..233	CDD:274055	46/169 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810