DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and Ctdsp1

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_001121551.1	Gene:	Ctdsp1 / 363249	RGDID:	1305629	Length:	261	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	63/236 - (26%)
Similarity:	104/236 - (44%)	Gaps:	57/236 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 AGVVKKRLRKE---GELLTKGDAILELSE------CIHT---TVIKD----MCADCGADLRQNEN 167
            :..|..::.||   |.|..|||....:|:      .:|:   .|.:|    :.|..||.|...||
  Rat     3 SSAVITQISKEEARGPLRGKGDQKSAVSQKPRSRGILHSLFCCVCRDDGEPLPAHSGAPLLVEEN 67

  Fly   168 GQTSEASVPMVHTMPDLKVTQKLAQKLGHDDTRRLLADRKLVLLVDLDQTVIHTT----NDT--- 225
            |...: ..|:.:.:|::|...                ..|:.:::|||:|::|::    |:.
  Rat    68 GAIPK-HTPVQYLLPEVKAQD----------------SDKICVVIDLDETLVHSSFKPVNNADFI 115

  Fly   226 VPDNIKGIYHFQLYGPHSPWYHTRLRPGTAEFLERMSQLYELHICTFGARNYAHMIAQLLDPEGK 290
            :|..|.|:.| |:|        ...||...|||:||.:|:|..:.|.....||..:|.|||..|.
  Rat   116 IPVEIDGVVH-QVY--------VLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGA 171

  Fly   291 FFSHRILSRDEC-FNATSKTDNLKALFPNGDSM--VCIIDD 328
            |.:.  |.|:.| |:..:...:|..|   |..:  |.|:|:
  Rat   172 FRAR--LFRESCVFHRGNYVKDLSRL---GRDLRRVLILDN 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	8/25 (32%)
		FCP1_euk	202..348	CDD:131304	41/137 (30%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
Ctdsp1	NP_001121551.1	HIF-SF_euk	90..249	CDD:274055	41/132 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810