DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and ttm50

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	NP_001303557.1	Gene:	ttm50 / 31266	FlyBaseID:	FBgn0250874	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	56/249 - (22%)
Similarity:	91/249 - (36%)	Gaps:	75/249 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 NGQTSE---ASVPMV-----HTMPDLKVTQKLAQ-----KLGHDDTRRLLADRKLVLLVDLDQTV 218
            |||..|   ...|:|     .....:...|::.|     ||..|..:......:..|::::...:
  Fly   175 NGQPIEDEFTHKPLVQQYLQRMWKSIHYYQRMIQEPSRAKLLPDPLKPPYVQPRYTLVLEMKDVL 239

  Fly   219 IHTTNDTVPDNIKGIYHFQLYGPHSPW-YHT----RLRPGTAEFLERMSQLYELHICTFGARNYA 278
            :|      ||                | |.|    :.|||...||...::.:|:.:.|.......
  Fly   240 VH------PD----------------WTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTV 282

  Fly   279 HMIAQLLDPEGKFFSHRILSRDECFNATSKTD-----NLKALFPNGDSMVCIIDDREDVWNMASN 338
            ..|...|||.| :..:|:: ||    ||...|     ||..|  |.|....|:.|    |:  :|
  Fly   283 FPILDALDPNG-YIMYRLV-RD----ATHFVDGHHVKNLDNL--NRDLKKVIVVD----WD--AN 333

  Fly   339 LIQVKPYHFFQHTGDINAPPGLSK-HELDGEG-----VDFKEITEKHGDKDKTE 386
            ..::.|.:.|          ||:: |..|.:|     :.|.:|..::...|..|
  Fly   334 ATKMHPDNTF----------GLARWHGNDDDGQLLDLIAFLKIIAQNNVDDVRE 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706
		FCP1_euk	202..348	CDD:131304	35/155 (23%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
ttm50	NP_001303557.1	CPDc	227..355	CDD:214729	40/173 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900