DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fcp1 and Ctdsp1

DIOPT Version :9

Sequence 1:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster
Sequence 2:	XP_036020359.1	Gene:	Ctdsp1 / 227292	MGIID:	2654470	Length:	302	Species:	Mus musculus

Alignment Length:	269	Identity:	66/269 - (24%)
Similarity:	107/269 - (39%)	Gaps:	82/269 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 AGVVKKRLRKE---GELLTKGDAILELSE------CIHT---TVIKD----MCADCGADLRQNEN 167
            :..|..::.||   |.|..|||....:|:      .:|:   .|.:|    :.|..||.|...||
Mouse     3 SSAVITQISKEEARGPLRGKGDQKSAVSQKPRSRGILHSLFCCVCRDDGEPLPAHSGAPLLVEEN 67

  Fly   168 GQTSEASVPMVHTMPDLKVTQKLAQKLGHDDTRRLLADRKLVLLVDLDQTVIHTT----NDT--- 225
            |...: ..|:.:.:|:.|...                ..|:.:::|||:|::|::    |:.
Mouse    68 GAIPK-HTPVQYLLPEAKAQD----------------SDKICVVIDLDETLVHSSFKPVNNADFI 115

  Fly   226 VPDNIKGIYHFQLYG-------------------------------PH--SPWYHTRLRPGTAEF 257
            :|..|.|:.| |.:|                               ||  .|..:...||...||
Mouse   116 IPVEIDGVVH-QEWGMVGAASLDCPSSSTVPVPLLWITPKPVGQQLPHWLVPQVYVLKRPHVDEF 179

  Fly   258 LERMSQLYELHICTFGARNYAHMIAQLLDPEGKFFSHRILSRDEC-FNATSKTDNLKALFPNGDS 321
            |:||.:|:|..:.|.....||..:|.|||..|.|.:.  |.|:.| |:..:...:|..|   |..
Mouse   180 LQRMGELFECVLFTASLAKYADPVADLLDKWGAFRAR--LFRESCVFHRGNYVKDLSRL---GRD 239

  Fly   322 M--VCIIDD 328
            :  |.|:|:
Mouse   240 LRRVLILDN 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	8/25 (32%)
		FCP1_euk	202..348	CDD:131304	44/170 (26%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
Ctdsp1	XP_036020359.1	HIF-SF_euk	90..290	CDD:274055	44/165 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810