Protein Alignment uri and Uri1

DIOPT Version :10

• Sequence 1: NP_611933.1
• Gene: uri / 37924
• FlyBaseID: FBgn0035025
• Length: 731
• Species: Drosophila melanogaster
• Sequence 2: NP_001100977.1
• Gene: Uri1 / 308537
• RGDID: 1310358
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 759
• Identity: 155/759 - (20%)
• Similarity: 245/759 - (32%)
• Gaps: 301/759 - (39%)

  Fly     4 REDALLQALQTNASE-TERWEAFKRDNESTIRNLDKFAKNLSVEVMVPIGRKALMPGELIHTNEL 67
            ||:.  :.:.||..| .:.||....|..:....|......||.::|||.|..|.|||:|:||||:
  Rat    32 REEQ--EKVVTNCQEKIQHWEKVDNDYSALQERLRTLPDKLSYDIMVPFGPLAFMPGKLVHTNEV 94

  Fly    68 LVGHYEGYFSACSSHKAKEICQYRLKLAEEQLKKLAVENDLWQKKLHTPFAEGAVPSGDQVEIVE 132
            .|...:.:|:.||:.:|..:.::|    :|.::|..  :|.  ||:...|.       .:||..|
  Rat    95 TVLLGDNWFAKCSAKQAVGLVEHR----KEHVRKTI--DDF--KKVLKNFE-------SRVEFTE 144

  Fly   133 DFNEESHNKW----LAEHRKRMRQQKQKERLEREAEPVKKDNEVLRKLEEREMMEELGLDPD-NI 192
            |..:.|....    :.|..|...:.|.|:|:..:.....|.:::.    |.|.  |.|:.|. ..
  Rat   145 DLQKMSDAAGDFVDIREEIKSDFEFKGKQRIAHKPHSKPKTSDIF----EAEF--ENGIKPQGTF 203

  Fly   193 DEDQLHDMLNQEPLKSTNESSPKSLTQEEE--DELWKKLEAEEQNEADELSSEAE-ESLKTTDNL 254
            |:|:|...|.:             |.::||  .||..|.:....|..|.:|||.| |...|..|:
  Rat   204 DDDELWARLEE-------------LERQEELLGELKSKPDTVIANGEDTVSSEEEKEDEDTGVNV 255

  Fly   255 VRQLMSGETETPSSKKRTAG---------TNRNVEIQDPISEDDGDDDDEGDQEEEVRTIREQMS 310
            |..:.  ::..|||.||..|         ::.|..:....|.....:|:|.::||:
  Rat   256 VSPVT--DSSAPSSCKRHGGNAGLPNGQTSSLNYSVNGSNSYHSNKEDEEEEEEED--------- 309

  Fly   311 LLPNEDREPFLRAQLHVLKAKMRKIQKVNFISDELIHLMNVVVMLEDDLQDLVFEQELEASEEEE 375
                                                         |||      ::|.:..|.:.
  Rat   310 ---------------------------------------------EDD------DEEDDDDESDH 323

  Fly   376 EVVENNHLPDEPSKELSTVSESSTNKRRISFALDDEKLEFRREETVAEMLPNAKKNSRDIIKLNA 440
            .|..:|.:|        |:..|.|
  Rat   324 AVSADNSIP--------TIYFSHT----------------------------------------- 339

  Fly   441 PLKPAGDPQPASIKTKRQTTQDILQKVERNIEFVKENQSVQDFDLLNRIMEESTGLINTLHISFT 505
                 .:|:...|.|.:.||....:|.|   |..::.:|.                      :.:
  Rat   340 -----VEPKRVRINTGKNTTLKFSEKKE---EAKRKRKSG----------------------AAS 374

  Fly   506 HSG----AIPSPSS------DQSDG--IPGKPSDFYVRYEKDRARPNDSFPIYVNGFEGEEHVKV 558
            ||.    ||.||:.      |..:|  ||.|      ...|.|:|.|.
  Rat   375 HSAHELPAIRSPADIYRVFVDVVNGEYIPRK------SILKSRSRENS----------------- 416

  Fly   559 PIMSEAARGSAYE---DPRSQFSKPNSSEICFTHSGSITPTSNDQSDDIPGNPFDFYEKYEKDRA 620
             :.|:.:..||.:   |.|:....|:|.|   |.:||.|..             :..|.:.|...
  Rat   417 -VCSDTSESSAADVDIDRRAPLRSPSSEE---TEAGSSTLE-------------ELQENHPKKPL 464

  Fly   621 KFSKSNSSEGDATDPESATKSILRNKSAVDLEPHNVNQQPKKGRKVRNQKKKERTLDDDLRDMSA 685
            ....|.:..|...:.|..:.|         |.||:.
  Rat   465 PSGVSEAFSGTVIEKEFLSPS---------LAPHSA----------------------------- 491

  Fly   686 YQKVMHDLVEKEPTAPEPLPPGKFIDSHA---PKKRVSRFKEQR 726
               :.|..:   ||.||    .|.:.|.|   |.||||:|:..|
  Rat   492 ---IAHHAL---PTIPE----RKEVLSEASEEPAKRVSKFRAAR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
uri	NP_611933.1	Prefoldin_URI1	1..113	CDD:467475	34/109 (31%)
		coiled coil	1..39	CDD:467475	9/35 (26%)
		PTZ00121	<144..>271	CDD:173412	34/130 (26%)
Uri1	NP_001100977.1	Prefoldin_URI1	28..151	CDD:467475	40/135 (30%)
		coiled coil	28..66	CDD:467475	9/35 (26%)
		coiled coil	109..149	CDD:467475	12/54 (22%)