DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11414 and AT3G62240

DIOPT Version :9

Sequence 1:	NP_611932.2	Gene:	CG11414 / 37923	FlyBaseID:	FBgn0035024	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	NP_191783.1	Gene:	AT3G62240 / 825397	AraportID:	AT3G62240	Length:	812	Species:	Arabidopsis thaliana

Alignment Length:	836	Identity:	215/836 - (25%)
Similarity:	321/836 - (38%)	Gaps:	222/836 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DNACVVCFKNVEIFSIGDCDH-PVCYECSTRMRVLCQQNECPICRHVLSKVLFTLDKLPYRELEA 108
            |::|.||..|:|..:.|.|.| .||..|..|:|.:.....|.||: ..|.::|....|.......
plant     2 DDSCAVCADNLEWVAYGSCGHREVCSTCVVRLRFVLDDPRCCICK-TESPIVFVTKALGDYTRTI 65

  Fly   109 NNRSDLYS--KKYRIG-FCTAEIRQQFFKLLDH----------PCPKCDAPPYRTFEG------- 153
            |:.|...|  ::.|:| |...|..|.||..||.          .|..||....:..||
plant    66 NDFSTFPSAPREGRVGAFWYHEDTQAFFDDLDQYRMIKAMCRLSCGVCDKTEDKPREGGPRHHRQ 130

  Fly   154 -------LRNHVRSEHKLLYCDLCVETLNIFTFERRCYTQAELQLHNTKGDPD---NRSHR---- 204
                   |:.|:..:|||..|.||:|...||..|::.||:|:|..|...||.:   :.|.|
plant   131 RIKSVEQLKGHLYHKHKLHMCGLCLEGRKIFICEQKLYTRAQLNQHIQTGDSEVDGSESERGGFA 195

  Fly   205 GHPLCEYCNKRYVDRDELFRHLRREHYFCHFCDAD--GCNEFYNDYADLAEHFRAEHFLCEEGKC 267
            |||:||:|...:...:||:.|:..|||.||.|...  |..|:|.:|.||..|||.:|||||:..|
plant   196 GHPMCEFCRNPFYGDNELYTHMSTEHYTCHLCQRSQPGQYEYYKNYDDLEIHFRRDHFLCEDDSC 260

  Fly   268 ATEQFVGAFRNEIEYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRND 332
            ..::|. .|:||.|.|.|.|..||..:::.|    |:..::|....|...|            ||
plant   261 LAKKFT-VFQNESELKRHNAIEHGGKMSRSQ----RSAALQIPTSFRYSRG------------ND 308

  Fly   333 EHNDYQNDLPSITQRHVSIDAGNEEQ----FPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLART 393
            :.|  :...|...:|    :.|:||.    ...||.:.:..|.....|||.|..
plant   309 QEN--RRGRPRSFRR----EPGDEEYNLAVHAALRLSESEYSRQEPAPPPSSAP----------- 356

  Fly   394 KENFPALGGGNGGGV--TGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVS 456
                |.....|...|  |.|....:.:.:.....|.:...:...|..|.|||.|
plant   357 ----PGFSENNNIHVDDTDPLIQPMESLSTTDMEPSSRYLQAVGSFGGGGSRLG----------- 406

  Fly   457 NRSAAVPKKAATPQVDFPALPGKGNKKNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASP 521
             .||            ||  |..|.:.:.:|:|.  ||:.:............|.|.   ::|||
plant   407 -ESA------------FP--PLSGQQSSGQNVES--LPTNTMAARLRRQTNRTSTAS---AIASP 451

  Fly   522 STFQKLQMVQKEEDEAKARQEALKKSAPKLTAAEFPSLGP-SASASSSRTTAPKPSSGSPSLNWS 585
            |  |...::.:                           || .||.:|....:   |||.|:
plant   452 S--QGWPVINR---------------------------GPGQASITSGGNHS---SSGWPA---- 480

  Fly   586 KPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQEQQANKKDKKQKDKKSNQENQPK- 649
                             :...||          :||:::||            .:..|:.:||:
plant   481 -----------------IGRTPV----------QASSSSVQ------------SRSHNRVSQPRP 506

  Fly   650 --TAKPK-ERNNNNEQKTNGAPSTPIRAPPGLKPGGPLKPPPGFVSNVTVNSVAKLPNNLTFTNS 711
              :|.|: .||.|....::.||:  :.....|:|.....||   ||:..|.      |..|.:.:
plant   507 LASAVPQAARNANRIPHSSSAPN--LSDTRSLQPSHSDFPP---VSSAVVQ------NRKTSSTT 560

  Fly   712 LGESYDIVPSPYTYTDPPDTEVRNQKLVDEVMSLLKTPE-ALNEFRLLSSKFRDGSCSGQAYYEH 775
            ...|.:..|       |||.:..|:.|::::.|.|...| ....||.:|.::|.||...:.|.|:
plant   561 TQGSSNTQP-------PPDVQSANKSLIEKMRSALGHDEDVFVAFRNISGQYRQGSIDAKTYLEY 618

  Fly   776 CQCAMLSSFYNLFPELLAMLPDISKQQELYLVHKQHL-------NSLPPAERKSVP 824
            .|...||   :|..:|..:.||..:|:||...|...|       |....|:..|.|
plant   619 VQGYGLS---HLVIDLARLCPDPKRQKELIDTHNASLREEDSKDNGRSAAQSSSQP 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11414	NP_611932.2	COG5236	2..>294	CDD:227561	98/285 (34%)
		zf-C3HC4_3	44..94	CDD:290631	18/49 (37%)
		DUF4187	<220..259	CDD:290533	18/40 (45%)
AT3G62240	NP_191783.1	COG5236	5..>308	CDD:227561	102/320 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	175	1.000	Domainoid score	I1101
eggNOG	1	0.900	-	-		E1_COG5236
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I1310
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1003372at2759
OrthoFinder	1	1.000	-	-		FOG0004142
OrthoInspector	1	1.000	-	-		otm3205
orthoMCL	1	0.900	-	-		OOG6_101580
Panther	1	1.100	-	-	LDO	PTHR22938
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2895
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830