DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nurf-38 and ppa1b

DIOPT Version :9

Sequence 1:	NP_523849.3	Gene:	Nurf-38 / 37922	FlyBaseID:	FBgn0016687	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001017833.1	Gene:	ppa1b / 550531	ZFINID:	ZDB-GENE-050417-375	Length:	291	Species:	Danio rerio

Alignment Length:	283	Identity:	161/283 - (56%)
Similarity:	208/283 - (73%)	Gaps:	2/283 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 TVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYANEEKTIYNMVVEVPRWTNAKMEISLKTPMNP 118
            |.|:|..|:.||.|||||..|..:||.||||::|:|.:.|::|||||||||||||||:.|.|:||
Zfish     5 TEERGNPNTLSYRLYFKNSNGKYLSPFHDIPMFADEAQNIFHMVVEVPRWTNAKMEIATKDPLNP 69

  Fly   119 IKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGCKGDNDPIDVIEIGYRVAKRG 183
            ||||:|||.||:|||.||||||||||||:|||||:|.|.:..|||.||||||||.|||.:|..||
Zfish    70 IKQDVKKGNLRYVANVFPHKGYIWNYGAIPQTWEDPGHKDNDTGCCGDNDPIDVCEIGSKVCSRG 134

  Fly   184 DVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIYKIPDG 248
            ||:||||||.:|:|||||||||:|||:|:||.|..:|:|:||.:..||.|.|||:||:.||:|||
Zfish   135 DVIKVKVLGVLAMIDEGETDWKVIAINVDDPEAKDLNNISDVRRLKPGYLEATVDWFRRYKVPDG 199

  Fly   249 KPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASGSISTTN--ITNRNSEHVIPKEEAEK 311
            ||||||||||:.|:.|||...|..||.||:.|:.|...:|.::..|  ::..||......:||:.
Zfish   200 KPENQFAFNGEFKDKDFAIETIKATHGFWKALLSQQTNAGELNCKNTCVSEGNSPFCCSADEAKA 264

  Fly   312 ILAEAPDGGQVEEVSDTVDTWHF 334
            ::..:...|....:..:||.|.:
Zfish   265 VVDGSCACGDASPIPTSVDKWFY 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:294149	152/237 (64%)
ppa1b	NP_001017833.1	pyrophosphatase	5..241	CDD:294149	152/235 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595974
Domainoid	1	1.000	284	1.000	Domainoid score	I1591
eggNOG	1	0.900	-	-		E1_COG0221
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5356
Inparanoid	1	1.050	346	1.000	Inparanoid score	I2287
OMA	1	1.010	-	-		QHG53511
OrthoDB	1	1.010	-	-		D1398991at2759
OrthoFinder	1	1.000	-	-		FOG0001608
OrthoInspector	1	1.000	-	-		otm25073
orthoMCL	1	0.900	-	-		OOG6_100346
Panther	1	1.100	-	-	LDO	PTHR10286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2162
SonicParanoid	1	1.000	-	-		X1018
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800