DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nurf-38 and Ppa2

DIOPT Version :9

Sequence 1:	NP_523849.3	Gene:	Nurf-38 / 37922	FlyBaseID:	FBgn0016687	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001129343.1	Gene:	Ppa2 / 310856	RGDID:	1307965	Length:	330	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	160/302 - (52%)
Similarity:	201/302 - (66%)	Gaps:	15/302 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 MALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYA---------------NEEKTIYNMVV 98
            |:||.|.|.|...|..|.|:||:..|:.|||.|||||.|               :|.|..:||||
  Rat    27 MSLYRTEELGHPRSKDYRLFFKHVAGHYISPFHDIPLKADCEEEHGIPRKKARNDEYKASFNMVV 91

  Fly    99 EVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGC 163
            |:||||||||||:.:.|:||||||.|.|:||:..|.||||||||||||||||||:|...:.||.|
  Rat    92 EIPRWTNAKMEIATEEPLNPIKQDTKNGRLRYTPNIFPHKGYIWNYGALPQTWEDPHLKDKSTNC 156

  Fly   164 KGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQY 228
            .||||||||.|||.:|..||||:.||:|||:||||:.|||||||||:||||.|.|.:||.||.::
  Rat   157 CGDNDPIDVCEIGSKVLSRGDVVHVKILGTLALIDQSETDWKIIAINVNDPEAEKFHDIDDVKKF 221

  Fly   229 FPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASGSISTT 293
            .||.|.|||.||::||:|||||||:|||||:.||..||..:|...|:.|:.:|.:....|:||..
  Rat   222 KPGYLEATVNWFRLYKVPDGKPENKFAFNGEFKNKAFALEVINSAHEHWKEMVMKKCDKGAISCV 286

  Fly   294 NITNRNSEHVIPKEEAEKILAEAPDGGQVEEVSDTVDTWHFI 335
            |:...:|......|||..::...|.....:|.|...:.|||:
  Rat   287 NVHICDSPFHCTTEEARSLVESIPTPSMSKESSVEEEVWHFL 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:294149	148/257 (58%)
Ppa2	NP_001129343.1	pyrophosphatase	23..284	CDD:294149	147/256 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353811
Domainoid	1	1.000	277	1.000	Domainoid score	I1656
eggNOG	1	0.900	-	-		E1_COG0221
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2384
OMA	1	1.010	-	-		QHG53511
OrthoDB	1	1.010	-	-		D1398991at2759
OrthoFinder	1	1.000	-	-		FOG0001608
OrthoInspector	1	1.000	-	-		otm45182
orthoMCL	1	0.900	-	-		OOG6_100346
Panther	1	1.100	-	-	LDO	PTHR10286
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1018
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770