DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nurf-38 and Ppa1

DIOPT Version :9

Sequence 1:	NP_523849.3	Gene:	Nurf-38 / 37922	FlyBaseID:	FBgn0016687	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	XP_038954538.1	Gene:	Ppa1 / 294504	RGDID:	1589773	Length:	311	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	154/311 - (49%)
Similarity:	206/311 - (66%)	Gaps:	22/311 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 MALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYANEEKT--------------------I 93
            |:.:.:.|:.|..:..|.::.||:.|..|||.||:|:||::...                    :
  Rat     1 MSSFSSEERAAPFTLEYRVFIKNEKGQYISPFHDVPIYADKMTNAFSTLKDQQQVWQSQESLADV 65

  Fly    94 YNMVVEVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIE 158
            ::||||||||:||||||:.|.|:||||||:||||||:|||.||:|||||||||:|||||:|.|.:
  Rat    66 FHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHSD 130

  Fly   159 PSTGCKGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIA 223
            ..|||.||||||||.|||.:|..||::::|||||.:|:|||||||||:|||:|:||.|:..:||:
  Rat   131 EHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETDWKVIAINVDDPDAANYHDIS 195

  Fly   224 DVDQYFPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASG 288
            ||::..||.|.|||:||:.||:|||||||:||||.:.||.:||..||..||.:|:.||.:.....
  Rat   196 DVERLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKNKEFAVDIIKNTHDYWKALVTKKTDGK 260

  Fly   289 SISTTNITNRNSEHVIPKEEAEKIL-AEAPDGGQVEEVSDTVDTWHFIHLK 338
            .||..|.|...|......:.|:.|: |..|.......:...||.| |.|.|
  Rat   261 GISCMNTTVSESPFKCDPDAAKAIVDALPPPCESACALPMDVDKW-FHHQK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:294149	140/262 (53%)
Ppa1	XP_038954538.1	pyrophosphatase	2..263	CDD:412231	138/260 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I1656
eggNOG	1	0.900	-	-		E1_COG0221
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5356
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2384
OMA	1	1.010	-	-		QHG53511
OrthoDB	1	1.010	-	-		D1398991at2759
OrthoFinder	1	1.000	-	-		FOG0001608
OrthoInspector	1	1.000	-	-		otm45182
orthoMCL	1	0.900	-	-		OOG6_100346
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1018
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740