DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nurf-38 and SPAC3A12.02

DIOPT Version :9

Sequence 1:	NP_523849.3	Gene:	Nurf-38 / 37922	FlyBaseID:	FBgn0016687	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_593328.1	Gene:	SPAC3A12.02 / 2542957	PomBaseID:	SPAC3A12.02	Length:	286	Species:	Schizosaccharomyces pombe

Alignment Length:	302	Identity:	138/302 - (45%)
Similarity:	185/302 - (61%)	Gaps:	40/302 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 AALASNCRYIQIERKRTKSHEMALYETVEKGAKNSPSYSLY-FKNKCGNVISPMHDIPLYANEEK 91
            |:||.|  .:|...|.|             |..|:|.:.:| :||  ...||..||:||  ..:|
pombe     2 ASLAKN--ILQFRSKIT-------------GKLNTPDFRVYCYKN--NKPISFFHDVPL--TSDK 47

  Fly    92 TIYNMVVEVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDH 156
            ..:|||.|:||||.||.||||.:|.:|||||:|.||||:|||.||:.|:||||||||||||:|:.
pombe    48 DTFNMVTEIPRWTQAKCEISLTSPFHPIKQDLKNGKLRYVANSFPYHGFIWNYGALPQTWEDPNV 112

  Fly   157 IEPSTGCKGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVND 221
            |:..|..|||.||:||.|||..:...|.:.:|||||.:.|||:|||||||:|||:|||.|..:||
pombe   113 IDSRTKMKGDGDPLDVCEIGGSIGYIGQIKQVKVLGALGLIDQGETDWKILAIDINDPRAKLLND 177

  Fly   222 IADVDQYFPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFW--------- 277
            |:||....|.||..|.:||.|||||||||:|:|.|:|:......|..|||:.|:.|
pombe   178 ISDVQNLMPRLLPCTRDWFAIYKIPDGKPKNRFFFDGNYLPKSDALDIIAQCHQHWKVSRDRKQY 242

  Fly   278 -QNLVHQSPASGSISTTNITNR-NSEHVIPKEEAEKILAEAP 317
             :|..::     |::..::.|: ||    .|||..:.::..|
pombe   243 IKNFHNE-----SVNNVDLINKINS----LKEEVSQNVSNYP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:294149	131/274 (48%)
SPAC3A12.02	NP_593328.1	pyrophosphatase	10..234	CDD:294149	124/240 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0221
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53511
OrthoFinder	1	1.000	-	-		FOG0001608
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100346
Panther	1	1.100	-	-	O	PTHR10286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2162
SonicParanoid	1	1.000	-	-		X1018
TreeFam	1	0.960	-	-
	9	8.810