DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nurf-38 and SPAC23C11.05

DIOPT Version :9

Sequence 1:	NP_523849.3	Gene:	Nurf-38 / 37922	FlyBaseID:	FBgn0016687	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_593636.1	Gene:	SPAC23C11.05 / 2542011	PomBaseID:	SPAC23C11.05	Length:	289	Species:	Schizosaccharomyces pombe

Alignment Length:	296	Identity:	158/296 - (53%)
Similarity:	200/296 - (67%)	Gaps:	21/296 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 MALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYANEEKTIYNMVVEVPRWTNAKMEISLK 113
            |:.|.|.|.||.|:..|.:|.: |.|..||..||||||||.||||.|||||:||||.||:||:.:
pombe     1 MSEYTTREVGALNTLDYQVYVE-KNGTPISSWHDIPLYANAEKTILNMVVEIPRWTQAKLEITKE 64

  Fly   114 TPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGCKGDNDPIDVIEIGYR 178
            ..:||||||.||||||||.|||||.||||||||.|||:|:|:.:.|.|..|||:||:||.|||..
pombe    65 ATLNPIKQDTKKGKLRFVRNCFPHHGYIWNYGAFPQTYEDPNVVHPETKAKGDSDPLDVCEIGEA 129

  Fly   179 VAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIY 243
            ....|.|.:|||||.:||:||||||||:|.||||||||.|:|||.||:::.|||:|||.|||:||
pombe   130 RGYTGQVKQVKVLGVMALLDEGETDWKVIVIDVNDPLAPKLNDIEDVERHMPGLIRATNEWFRIY 194

  Fly   244 KIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLV-HQSPASGSISTTNITNRN-------- 299
            |||||||||.|||:|:.||..:|..::.|.::.|:.|: .::.|....|..|::...
pombe   195 KIPDGKPENSFAFSGECKNRKYAEEVVRECNEAWERLITGKTDAKSDFSLVNVSVTGSVANDPSV 259

  Fly   300 SEHVIPKEEAEKILAEAPDGGQVEEVSDTVDTWHFI 335
            |..:.|.:|    ||.||       |..:|..|.:|
pombe   260 SSTIPPAQE----LAPAP-------VDPSVHKWFYI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nurf-38	NP_523849.3	pyrophosphatase	26..292	CDD:294149	145/243 (60%)
SPAC23C11.05	NP_593636.1	pyrophosphatase	2..240	CDD:294149	144/238 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I360
eggNOG	1	0.900	-	-		E1_COG0221
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5356
Inparanoid	1	1.050	310	1.000	Inparanoid score	I579
OMA	1	1.010	-	-		QHG53511
OrthoFinder	1	1.000	-	-		FOG0001608
OrthoInspector	1	1.000	-	-		oto101026
orthoMCL	1	0.900	-	-		OOG6_100346
Panther	1	1.100	-	-	LDO	PTHR10286
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2162
SonicParanoid	1	1.000	-	-		X1018
TreeFam	1	0.960	-	-
	13	12.950