Protein Alignment CG4622 and zcchc8

DIOPT Version :10

• Sequence 1: NP_611929.1
• Gene: CG4622 / 37919
• FlyBaseID: FBgn0035021
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001077287.1
• Gene: zcchc8 / 553372
• ZFINID: ZDB-GENE-060526-6
• Length: 692
• Species: Danio rerio
• Alignment Length: 716
• Identity: 175/716 - (24%)
• Similarity: 265/716 - (37%)
• Gaps: 218/716 - (30%)

  Fly     9 DDSQNSVVIVDDDVEDGELED------DVVFVCPEELTRKEIE-------------PPTDKIEE- 53
            :|..::.:..:...|:||..|      ..:..|.|.:.|...|             |....||:
Zfish    16 EDKASARITDEGGEEEGESSDRLQGLRQTLGECEETIGRLNAENEELKRKLNILSRPMGITIEDS 80

  Fly    54 ---------KHSNTSIQDTTEEDGDSLVFEVRFNKEAH----FTSLQQQVLVALEGAFADKQIVF 105
                     .:.|..|......:.:..:|.: ..|:.|    ..|....|..|.....|:...|.
Zfish    81 KTSGPVCQINYGNNIISRQCRNEIEDFIFSL-VQKQLHNNDREASTPHVVPHASSFVMAESYKVK 144

  Fly   106 RDNPQELMISAF---------------ERSRTLPEEEPQDLFLIDTQPAAKLNAANVPSYKRCNA 155
            ..:..:|:.:||               :..:.|..|.||           :.....||.|::...
Zfish   145 TSSDSKLIKNAFTVIGSVLYFTDFCVDKLGQPLMNESPQ-----------QTEGWEVPKYQQVFG 198

  Fly   156 DI--LDEQTEERKKLKAEAVNKCFRPKAQSSCFNCGDTEHSLRDCTKPRNNSRITRARKKMTSR- 217
            .|  |:.|..|.|:.         |||  ..||||...:|.||||.||::.:||...||:.:..
Zfish   199 QIIALEGQDVEIKQK---------RPK--PCCFNCCSEDHQLRDCPKPKDMARINEKRKEFSQNN 252

  Fly   218 --TERYHV-DTEQRFGHIRPGKISTKTRHAMGYSRGQLPFIFYRMRVLGYPPAWLEEAKVQSSGI 279
              .:|||. :.|:||...:||.:|.....|:|.:...||...||||.|||||.||:||::::||:
Zfish   253 QSNQRYHAEEVEERFAKYKPGIMSQDLLDALGMTTNTLPPFIYRMRELGYPPGWLKEAELENSGL 317

  Fly   280 ALFNADGSEVTKSDEEEGESETFKYDVNKIVEYPGFNVQPKANCFDDFKHHNVPPFQESQSKENF 344
            .|:  |||   ...:|...|:...|||:|:|::|||||....|..||::.....|.|....|:||
Zfish   318 MLY--DGS---NDGDENNHSQKISYDVSKLVDFPGFNVNAPPNIRDDYRSFGSIPMQPQHWKQNF 377

  Fly   345 IKSLGENVINGYKRKKLVDLPAPH--DRVPAPSELLTSFDDY-----DMELEEETE--------- 393
            ...|.    |.:..:.......||  |..|..::...|..|.     |||:|.:.:
Zfish   378 AAFLS----NTFPTQDSGSSKRPHESDSTPQKTKKRKSGSDQTLQASDMEIESDHDMPQMRSDGF 438

  Fly   394 --DPPLPP-------------SVPPPQPP---------PP---------------EECEDGELTA 419
              .|||||             ..||..||         ||               ||.||| ||
Zfish   439 QFHPPLPPGTSSIGTPPPLPLGTPPSTPPIPKGTPPATPPTNENPSTHARAQTEGEESEDG-LT- 501

  Fly   420 RSPSPSLEDLKAQQEELLQELDVNASHNTTANESKSPT------------DLDD----------T 462
                  ||:|:.||..|...|:  .:..||.::|.:|.            |.:|          |
Zfish   502 ------LEELEEQQRLLWAALE--KADTTTNSDSDTPVPSSPSVVTSLKFDTEDDGEKMEDSIHT 558

  Fly   463 SETEVGPSA---------------------------------------AESGNNEQSRSAPSTPF 488
            .|.:..||:                                       .|:||.:.|.:......
Zfish   559 FEIKSTPSSPAVSNVCEDEMTDKTNSDGKQEIDLQAEMSDIIVLDEVYGENGNPDASDAPQKNVQ 623

  Fly   489 KASYEGTPLLKFSVYDR---LPVGSNFKVGV---SDVINFENLPDSTGKYEQMKDLLKNVREKMV 547
            ::|.|....::.|..::   :|..|.|..|:   .|...|..:.::||.|.:::||||.......
Zfish   624 ESSSEVADDIEESGVNKVTFVPHRSRFAAGIIPFEDTPEFTEVAEATGVYLKIRDLLKGSPRNQA 688

  Fly   548 K 548
            |
Zfish   689 K 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4622	NP_611929.1	PSP	229..281	CDD:128850	23/51 (45%)
zcchc8	NP_001077287.1	PSP	271..317	CDD:461145	21/45 (47%)