Protein Alignment CG4622 and Zcchc8

DIOPT Version :10

• Sequence 1: NP_611929.1
• Gene: CG4622 / 37919
• FlyBaseID: FBgn0035021
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001387897.1
• Gene: Zcchc8 / 288661
• RGDID: 1309774
• Length: 695
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 181/688 - (26%)
• Similarity: 290/688 - (42%)
• Gaps: 193/688 - (28%)

  Fly     9 DDSQNSVVIVDDDVEDG----ELEDDVVFVCPEELTRKEIEPPTDKIEEK-----------HSNT 58
            ||.:..    |||.|:|    ||::. :..|.|  |.:::.....:::.|           .|||
  Rat    33 DDEEED----DDDDENGVGDAELQEQ-LRRCEE--TIEQLRAENQELKRKLNILTRPSGILVSNT 90

  Fly    59 SIQDTTEEDGDSLVFEVRFNKEAHFTSLQQQV---LVALEGAFADKQIVFRDNPQELMISAFERS 120
            .|        |..:.::.|...|......|::   :..|...|.::|   :::.::...|...:.
  Rat    91 KI--------DGPLLQILFMNNAISKQYHQEIEEFVSNLVKRFEEQQ---KNDVEKTSFSLLPQP 144

  Fly   121 RTLPEEEPQDL------------------------FLIDT--QPAAKLNAA-----NVPSYKRCN 154
            .::..||.:.:                        |.:|.  ||....|..     .:|.|::..
  Rat   145 SSVMLEEDRKVEESCAIKNNKEAFSVVGSVLYFTNFCLDKLGQPLLNENPQLTEGWEIPKYQQVF 209

  Fly   155 ADILDEQTEERKKLKAEAVNKCFRPKAQSSCFNCGDTEHSLRDCTKPRNNSRITRARKK------ 213
            :.|:..:.:| .::||:      |||..  |||||..||.:::|..|||.:||:..||:
  Rat   210 SHIVSLEGQE-MQVKAK------RPKPH--CFNCGSEEHQMKECPMPRNAARISEKRKEYMDACG 265

  Fly   214 ---MTSRTERYHV-DTEQRFGHIRPGKISTKTRHAMGYSRGQLPFIFYRMRVLGYPPAWLEEAKV 274
               ..|..:|||. :.|:|||..:||.||.:.:.|:|.:...||...||||.|||||.||:||::
  Rat   266 EANSQSFQQRYHAEEVEERFGRFKPGVISEELQDALGVTDKSLPPFIYRMRQLGYPPGWLKEAEL 330

  Fly   275 QSSGIALFNADGSEVTKSDEEEGESET-------FKYDVNKIVEYPGFNVQPKANCFDDFKHHNV 332
            ::||:||:  ||     :|:.:||:||       ..||::|:|.|||||:.......|:::....
  Rat   331 ETSGLALY--DG-----NDDADGETETGEIQNKNVTYDLSKLVNYPGFNISTPRGIPDEWRMFGS 388

  Fly   333 PPFQESQSKENFIKSLGENVINGYKR---KKLVDLPAPHDRVPAPSELLTSFDDYDMELEEETE- 393
            .|.|..|.|:.|...|..|:.:...:   |:.....:|:.......|...:....||||:.:.|
  Rat   389 IPMQACQQKDVFASYLNSNIQSPSVKSSSKRSSSQSSPNSPKKQRREGSAAASPADMELDSDIEI 453

  Fly   394 ------------DPPLPPSVPPPQP---PPP---EECEDG--ELT-ARSPSP------------S 425
                        .|||||..|||.|   |||   .....|  .|| :.||.|            :
  Rat   454 PPGSQSSKAFQFQPPLPPGTPPPLPQGTPPPLFTPPLPKGTPPLTPSDSPQPRPTASGVDEDALT 518

  Fly   426 LEDLKAQQEEL---LQE-----------LDVNASHNTTANESKSPTDLD---------------- 460
            ||:|:.||.::   ||:           :|...:.|:.|: |..|.:.|
  Rat   519 LEELEEQQRQIWAALQQAEGANSDSDVPMDTPLTGNSVAS-SPCPNEFDLRVPEGRALEKPVLAE 582

  Fly   461 -DTSETEVGPS---AAES---GNNEQSRSAPSTPFKASYEGTPLLKFS---------------VY 503
             ||:..|  ||   |||:   ...|:..||...|.....:...:|..|               .:
  Rat   583 PDTASPE--PSCSPAAEAAVLSQKEEGVSAEGDPGDGLLDNGGVLNISNGGNHLDTRPPTASKTH 645

  Fly   504 DRLPVGSNFKVGVSDVINFENLPDSTGKYEQMKDLLKN 541
            ..:|..|.|..|::. ..|||:.:|||.|.::::||||
  Rat   646 SPVPDMSKFAHGITP-FEFENMAESTGMYLRIRNLLKN 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4622	NP_611929.1	PSP	229..281	CDD:128850	25/51 (49%)
Zcchc8	NP_001387897.1	zf-CCHC	229..246	CDD:395050	8/18 (44%)
		PSP	285..337	CDD:470641	25/51 (49%)