DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and MIP6

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_011879.1	Gene:	MIP6 / 856408	SGDID:	S000001057	Length:	659	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	42/205 - (20%)
Similarity:	82/205 - (40%)	Gaps:	42/205 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 IYIKNL---ERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNG- 175
            ::..||   ...:..::.|.....:||:|:|.:.:     .:..|||:||::.:||..|:|.|.
Yeast   201 VFFSNLPLENPQLTTRSFYLIMIEYGNVLSCLLER-----RKNIGFVYFDNDISARNVIKKYNNQ 260

  Fly   176 ------MLCNNQKVHVVKFIPRRDREQEKA----------------------THFKNLYVKNLSE 212
                  ::|.   :|..|.:..|....::.                      ...|.:.||||..
Yeast   261 EFFGNKIICG---LHFDKEVRTRPEFTKRKKMIGSDIVIEDELLASNNLSDNARSKTILVKNLPS 322

  Fly   213 EFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVA 277
            :.|::.:.:.|...|.|.| ..:.:::..:....||.|:|.:.:..|...|: |.:..|..::|.
Yeast   323 DTTQEEVLDYFSTIGPIKS-VFISEKQANTPHKAFVTYKNEEESKKAQKCLN-KTIFKNHTIWVG 385

  Fly   278 RALSKAERQQ 287
            ....|....|
Yeast   386 PGKDKPVHNQ 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	18/79 (23%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	19/79 (24%)
MIP6	NP_011879.1	RRM	8..>187	CDD:223796
		RRM1_PES4_MIP6	111..190	CDD:410180
		RRM2_PES4_MIP6	200..275	CDD:410181	19/81 (23%)
		RRM3_PES4_MIP6	313..385	CDD:410182	18/73 (25%)
		RRM4_PES4_MIP6	400..478	CDD:410183
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010