DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and NSR1

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_011675.1	Gene:	NSR1 / 853064	SGDID:	S000003391	Length:	414	Species:	Saccharomyces cerevisiae

Alignment Length:	168	Identity:	40/168 - (23%)
Similarity:	79/168 - (47%)	Gaps:	11/168 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 IYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLC 178
            |::..|..|||::.:...|...|.::...|..:. ...|||||:|.|:::..|..||:::.|...
Yeast   170 IFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEI 234

  Fly   179 NNQKVHVVKFIPRRDREQEKATHF--------KNLYVKNLSEEFTEQHLREMFEPYGRITSHKLM 235
            :.:.::......:.....::|..|        ..|::.|||.......:.|:|..:|.:.|.::.
Yeast   235 DGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIP 299

  Fly   236 L-DEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNK 272
            . .|..:.:.||:|.:.|.:.|..|:..|.|:.: ||:
Yeast   300 THPETEQPKGFGYVQFSNMEDAKKALDALQGEYI-DNR 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/70 (27%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	20/80 (25%)
NSR1	NP_011675.1	RRM1_gar2	169..244	CDD:409881	19/73 (26%)
NSR1	NP_011675.1	RRM2_gar2	269..341	CDD:409882	19/69 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870