DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and ML2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_565990.1	Gene:	ML2 / 818890	AraportID:	AT2G42890	Length:	843	Species:	Arabidopsis thaliana

Alignment Length:	193	Identity:	45/193 - (23%)
Similarity:	85/193 - (44%)	Gaps:	19/193 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 NSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIE 171
            |....|..::::|:..|:::..:...|..||.|.:...|    ..|||:..:.:....||.||:.
plant   192 NGEHPSRTLFVRNINSSVEDSELSALFEPFGEIRSLYTA----CKSRGFVMISYYDIRAAHAAMR 252

  Fly   172 KVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLML 236
            .:...|...:.:.:...|| ::...||..:...|.:.|:....:...|.::|..||.|...:
plant   253 ALQNTLLRKRTLDIHFSIP-KENPSEKDMNQGTLVIFNVDTTVSNDELLQLFGAYGEIREIR--- 313

  Fly   237 DEEGRSRRF-GFVAYENPQSALAAVIGLHGKQLGDNKFLYV-------ARALSKAERQQEINR 291
              |..:||| .|:.|.:.:.|..|:..|:..::| .|.:.:       ||.||...:.|::.|
plant   314 --ETPNRRFHRFIEYYDVRDAETALKALNRSEIG-GKCIKLELSRPGGARRLSVPSQSQDLER 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	15/69 (22%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	21/87 (24%)
ML2	NP_565990.1	PABP-1234	<149..471	CDD:130689	45/193 (23%)
		RRM1_MEI2_like	197..273	CDD:409944	18/80 (23%)
		RRM2_MEI2_like	282..352	CDD:409948	18/75 (24%)
		RRM_2	679..775	CDD:112856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910