DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and celf4

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_031757481.1	Gene:	celf4 / 779831	XenbaseID:	XB-GENE-5873699	Length:	488	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	68/257 - (26%)
Similarity:	107/257 - (41%)	Gaps:	44/257 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 AAAVLGRHGHNSLGS---GHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGKIYIKNLER 122
            |....|:..::||.|   ||.:..:||.      ||.|...        ....|:.|::|..:.|
Frog     6 ATVANGQPDNSSLSSNPTGHMNGLTHSP------GGAATIP--------MKDHDAIKLFIGQIPR 56

  Fly   123 SIDNKAVYDTFSVFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVV 186
            ::|.|.:...|..||.|....|.||. .|..:|..|:.:...|:|..|          ...:|..
Frog    57 NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKA----------QSALHEQ 111

  Fly   187 KFIPRRDR-------EQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRR 244
            |.:|..:|       :.|.....:.|:|..|:::.:|..:|.:||.:|.|....::...:|.|:.
Frog   112 KTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKG 176

  Fly   245 FGFVAYENPQSALAAVIGLHGKQL--GDNKFLYVARALSKAERQQEINRKLEERKRQKAGQI 304
            ..||.|.:...|.||:..|||.|.  |.:..|.|..|.:..||..       .|.:|.|||:
Frog   177 CAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTM-------RRMQQMAGQM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	17/70 (24%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	25/81 (31%)
celf4	XP_031757481.1	RRM1_CELF3_4_5_6	42..128	CDD:410041	23/95 (24%)
		RRM2_CELF3_4_5_6	134..214	CDD:410043	24/79 (30%)
		RRM3_CELF3_4_5_6	399..477	CDD:241083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910