DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and ncl

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001070120.2	Gene:	ncl / 767714	ZFINID:	ZDB-GENE-030131-6986	Length:	705	Species:	Danio rerio

Alignment Length:	225	Identity:	59/225 - (26%)
Similarity:	102/225 - (45%)	Gaps:	39/225 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 GHTSTSSHSANV----------------GVGVGGGALASGSTGG---SGGNSSPDSGKIYIKNLE 121
            |:|.||...|.:                |..|.|.::....||.   .||..:|.:.|:.:.|
Zfish   408 GNTGTSRGIAYIEFKTEAIAEKALEEAQGSDVQGRSIIVDFTGDKSRQGGRGAPSASKVLVVN-- 470

  Fly   122 RSIDNKAVYDTF-SVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVH- 184
             ::...|..|:. |||...::..:.:: :|..:||.||.|::.|.::.|:|.     |||..:.
Zfish   471 -NLAFSASEDSLQSVFEKAVSIRIPQN-NGRPKGYAFVEFENVEDSKEALEN-----CNNTDIEG 528

  Fly   185 --VVKFIPRRDRE-----QEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRS 242
              :.....:.|||     :..:...|.|:||.||::.|:|.|::.|:  |.|.:......:.|.|
Zfish   529 RSIRLEYSQNDRERGGGGRGNSGPTKTLFVKGLSDDTTDQTLKDSFD--GAIAARIATDRDTGSS 591

  Fly   243 RRFGFVAYENPQSALAAVIGLHGKQLGDNK 272
            :.||||.::|.|...||...:...::..||
Zfish   592 KGFGFVDFDNEQDCKAAKEAMDDGEIDGNK 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	18/73 (25%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	24/71 (34%)
ncl	NP_001070120.2	RRM1_NCL	287..361	CDD:240849
		RRM	347..630	CDD:223796	59/225 (26%)
		RRM2_NCL	374..450	CDD:240850	8/41 (20%)
		RRM3_NCL	464..535	CDD:240851	19/79 (24%)
		RRM4_NCL	554..631	CDD:240852	24/70 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910