DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Celf6

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_006511603.1	Gene:	Celf6 / 76183	MGIID:	1923433	Length:	481	Species:	Mus musculus

Alignment Length:	238	Identity:	62/238 - (26%)
Similarity:	107/238 - (44%)	Gaps:	38/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 GGGALASG-------STGGSGG-----NSSP-------DSGKIYIKNLERSIDNKAVYDTFSVFG 137
            ||.|..:|       ||..|||     |..|       |:.|:::..:.|.:|.:.:...|..||
Mouse     6 GGSAPPAGPSPRLAFSTADSGGGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFG 70

  Fly   138 NILNCNVAKDE-DGNSRGYGFVHF---DSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEK 198
            .|....|.||. .|..:|..|:.:   ||...|::|:.:...:...|:.:.|      :....|.
Mouse    71 RIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQV------KPAASEG 129

  Fly   199 ATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGL 263
            ....:.|:|..|.::..|:.:|.:|:|:|.|....::...:|.|:...||.:.:...|.||:.||
Mouse   130 RGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIQGL 194

  Fly   264 HGKQ--LGDNKFLYVARALSKAERQQEINRKLEERKRQKAGQI 304
            ||.:  .|.:..|.|  .|:..:|::.:     .|.:|.|||:
Mouse   195 HGSRTMTGASSSLVV--KLADTDRERAL-----RRMQQMAGQL 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	17/73 (23%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	24/81 (30%)
Celf6	XP_006511603.1	RRM1_CELF3_4_5_6	41..127	CDD:241076	20/91 (22%)
		PABP-1234	<48..390	CDD:130689	49/196 (25%)
		RRM2_CELF3_4_5_6	133..213	CDD:241079	24/81 (30%)
		RRM3_CELF3_4_5_6	392..470	CDD:241083
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910