DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Pabpc5

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001103836.1	Gene:	Pabpc5 / 688518	RGDID:	1587661	Length:	382	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	88/202 - (43%)
Similarity:	127/202 - (62%)	Gaps:	15/202 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 SSPDS-------GKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEA 165
            |.||.       |.|:||||::||||:|::..||.|||||:|.|..|::| |:||.:|||||..|
  Rat    94 SQPDDHLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNG-SKGYAYVHFDSLAA 157

  Fly   166 ARAAIEKVNGMLCNNQKVHVVKF-IPRRD----REQEKATHFKNLYVKNLSEEFTEQHLREMFEP 225
            |..||..:||:..||::|:|.:| .|...    |.:::|| |.|::|||..::..::.|:::|..
  Rat   158 ANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRAT-FTNVFVKNFGDDIDDEKLKKLFSE 221

  Fly   226 YGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEIN 290
            ||...|.|::.|..|:|:.||||.||..::|..||:.||||.: |.|.|.|.||..|.||..|:.
  Rat   222 YGPTESVKVIRDATGKSKGFGFVRYETHEAAQKAVLELHGKSI-DGKVLCVGRAQKKIERLAELR 285

  Fly   291 RKLEERK 297
            |:.|..|
  Rat   286 RRFERLK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	38/69 (55%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	33/79 (42%)
Pabpc5	NP_001103836.1	RRM1_I_PABPs	22..98	CDD:240824	2/3 (67%)
		ELAV_HUD_SF	29..271	CDD:273741	78/179 (44%)
		RRM2_I_PABPs	104..179	CDD:240825	40/75 (53%)
		RRM3_I_PABPs	198..277	CDD:240826	33/79 (42%)
		RRM_SF	301..377	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52254
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.120