DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4612 and RBM4

DIOPT Version :9

Sequence 1:NP_001246493.1 Gene:CG4612 / 37914 FlyBaseID:FBgn0035016 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_002887.2 Gene:RBM4 / 5936 HGNCID:9901 Length:364 Species:Homo sapiens


Alignment Length:169 Identity:45/169 - (26%)
Similarity:78/169 - (46%) Gaps:22/169 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   114 KIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLC 178
            |::|.||.|....:.:...|..:|.:|.|::.|:       |||||.:.:.||..||..:     
Human     3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN-------YGFVHIEDKTAAEDAIRNL----- 55

  Fly   179 NNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSR 243
            ::.|:|.|.......:.:.|.:  ..|:|.|:|...|.:.||..||.||.:....::.|      
Human    56 HHYKLHGVNINVEASKNKSKTS--TKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD------ 112

  Fly   244 RFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSK 282
             :.||..|..:.|:.|:.||...:. ..|.::|..:.|:
Human   113 -YAFVHMERAEDAVEAIRGLDNTEF-QGKRMHVQLSTSR 149

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4612NP_001246493.1 RRM2_I_PABPs 115..185 CDD:240825 19/69 (28%)
RRM3_I_PABPs 202..282 CDD:240826 21/79 (27%)
RBM4NP_002887.2 RRM1_RBM4 2..68 CDD:410018 22/76 (29%)
RRM2_RBM4 78..144 CDD:410019 20/73 (27%)
PTZ00368 <145..>181 CDD:173561 1/5 (20%)
ZnF_C2HC 161..176 CDD:197667
Interaction with TNPO3. /evidence=ECO:0000269|PubMed:12628928 196..364
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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