DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and rbm4.1

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_955999.1	Gene:	rbm4.1 / 573001	ZFINID:	ZDB-GENE-030131-3902	Length:	419	Species:	Danio rerio

Alignment Length:	155	Identity:	45/155 - (29%)
Similarity:	70/155 - (45%)	Gaps:	31/155 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEK-----V 173
            ||::.||..:...:.:...||.:|.|..|::.|:       :||||.||:..|..||:.     :
Zfish     3 KIFVGNLSPNTTAEEIRSLFSQYGKISECDIVKN-------FGFVHMDSKSEADEAIQNLHHYML 60

  Fly   174 NGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE 238
            |||..|   |.:.|..|:...:.         :|.|:|...|.|.||..||.||.:....::.|
Zfish    61 NGMAMN---VEMSKGKPKTSTKP---------HVGNISSSCTNQELRAKFEEYGPVVECDIVKD- 112

  Fly   239 EGRSRRFGFVAYENPQSALAAVIGL 263
                  :.||..|..:.|:.|:.||
Zfish   113 ------YAFVHMERVEDAMEAISGL 131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	23/74 (31%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	19/62 (31%)
rbm4.1	NP_955999.1	RRM1_RBM4	2..68	CDD:241050	23/74 (31%)
		RRM2_RBM4	78..144	CDD:241051	19/70 (27%)
		ZnF_C2HC	161..176	CDD:197667
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	322..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910